Asialo-Ganglioside GM1 ≥98% (by TLC)
Supplier: ADIPOGEN CORP MS
Synonyms:
Ceramide tetrahexoside
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Removing the sialic acid from monosialoganglioside GM1 inhibits its ability to bind cholera toxin. Asialo-ganglioside GM1 does not block the binding of cholera toxin to cellular GM1.
Formula:
C₆₂H₁₁₄N₂O₂₃ MW: 1255.6 g/mol (calc. on sphingosine C18:1 and stearic acid) Storage Temperature: Freezer |
CAS Number:
71012-19-6 |
Specification Test Results
Source/Host | Semisynthetic. |
Purity |
|
Solubility | Soluble in chloroform:methanol (2:1). |
Formulation | Lyophilized. |
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