You Searched For: DL-3-Aminobutyric+acid

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Anti-ARMET Rabbit Polyclonal Antibody

Catalog Number: (75929-844)

Supplier: Rockland Immunochemical

Description: MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.

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DL-Tartaric acid for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma

Description: DL-Tartaric acid for synthesis, Sigma-Aldrich®

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Anti-GADL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10284-392)

Supplier: Bioss

Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.

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Anti-GABRB2 Rabbit Polyclonal Antibody

Catalog Number: (10075-714)

Supplier: Prosci

Description: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.

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DL-Malic acid 99+%

Catalog Number: (TS12525-0050)

Supplier: Thermo Scientific Chemicals

Description: DL-Malic acid 99+%

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DL-α-Aminoadipic acid 97%

Supplier: Ambeed

Description: DL-α-Aminoadipic acid 97%

Anti-GABARAPL1 Rabbit Polyclonal Antibody

Catalog Number: (76075-832)

Supplier: Prosci

Description: For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50

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DL-Leucic acid

Supplier: Spectrum Chemicals

Description: DL-Leucic Acid, Purity: 98.0 %, Cas number: 10303-64-7, Molecular formula: C6H12O3, Molecular Weight: 132.16, Color/Appearance: White, Off-white, Crystals, Powder, Synonyms: 2-Hydroxy-4-methylvaleric Acid, Size: 100G

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