You Searched For: Carboplatin


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Supplier: Thermo Scientific Chemicals
Description: An antitumor agent
Supplier: Adipogen
Description: Potent platinum-based antineoplastic agent. Analog of cisplatin (Prod. No. AG-CR1-3590) with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.

Supplier: Ambeed
Description: Carboplatin 99%

Catalog Number: (100206-812)
Supplier: Strem Chemicals Inc
Description: CAS #: 41575-94-4. Size: 0.25g.


Supplier: Enzo Life Sciences
Description: Antitumor agent.

Supplier: TCI America
Description: CAS Number: 41575-94-4
Molecular Formula: C6H12N2O4Pt
Molecular Weight: 371.26
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Catalog Number: (77694-021)
Supplier: LGC STANDARDS
Description: Carboplatin-d4, TRC, LGC Standards

New Product


Supplier: Adipogen
Description: Potent platinum-based antineoplastic agent with wide spectrum anticancer activity. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Shows antitumor activity in cisplatin resistant cell lines. Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. AG-CR1-3590) and carboplatin (Prod. No. AG-CR1-3591). Apoptosis inducer. Targets other proteins and enzymes. Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2. Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake.

Supplier: Adipogen
Description: Antagonizing the Chk1-mediated cell cycle checkpoints has emerged as an attractive target for anticancer therapy. If Chk1 activity is blocked, DNA-damaged or spindle-disrupted cells would exit cell cycle arrest before full repair and subsequently undergo mitotic catastrophe or cell death. Chk1 inhibitors consequently increase the therapeutic index of DNA-damaging or antimitotic agents as well. PF-0477736 is a selective, potent ATP-competitive Chk1 inhibitor, derived from PF-0394691, inhibits Chk1 (Ki, 0.49nM) and Chk2 (Ki, 47nM) in vitro. In tests, PF-0477736 was identified as a potent, selective ATP-competitive small-molecule inhibitor that inhibits Chk1 with a Ki of 0.49nM. PF-0477736 abrogates cell cycle arrest induced by DNA damage and enhances cytotoxicity of clinically important chemotherapeutic agents, including gemcitabine and carboplatin. In xenografts, PF-0477736 enhanced the antitumor activity of gemcitabine in a dose-dependent manner. PF-0477736 combinations were well tolerated with no exacerbation of side effects commonly associated with cytotoxic agents.

Catalog Number: (220113-083)
Supplier: Sigma Aldrich
Description: CARBOPLATIN

Blocked

Catalog Number: (220113-082)
Supplier: Sigma Aldrich
Description: CARBOPLATIN

Blocked

Catalog Number: (103961-842)
Supplier: ASTATECH INC MS
Description: CARBOPLATIN 5G

Blocked

Catalog Number: (103961-840)
Supplier: ASTATECH INC MS
Description: CARBOPLATIN 1G

Blocked

Catalog Number: (102871-390)
Supplier: R&D Systems
Description: CARBOPLATIN (50 MG)


Catalog Number: (103961-838)
Supplier: ASTATECH INC MS
Description: CARBOPLATIN 0.25G

Blocked

Catalog Number: (101096-452)
Supplier: USP
Description: CARBOPLATIN 100MG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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