Oxaliplatin

Supplier: ADIPOGEN CORP MS

Synonyms: (trans-1,2-Cyclohexanediamine)oxalatoplatinum(II), Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)

AG-CR1-3592-M005 AG-CR1-3592-M025 AG-CR1-3592-M100

102988-690EA 27.69 USD

102988-690 102988-692 102988-694

Oxaliplatin

Oxaliplatin

Potent platinum-based antineoplastic agent with wide spectrum anticancer activity. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Shows antitumor activity in cisplatin resistant cell lines. Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. AG-CR1-3590) and carboplatin (Prod. No. AG-CR1-3591). Apoptosis inducer. Targets other proteins and enzymes. Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2. Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake.

Formula: C₈H₁₄N₂O₄Pt
MW: 397.29 g/mol

MDL Number: MFCD00866327
CAS Number: 61825-94-3

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