You Searched For: Tamoxifen+citrate

Supplier: Thermo Scientific Chemicals

Description: Tamoxifen citrate 98%

Catalog Number: (80057-564)

Supplier: MilliporeSigma

Description: Tamoxifen Citrate is a potent, synthetic, anti-estrogen

Certificates

Catalog Number: (101907-994)

Supplier: Matrix Scientific

Description: Matrix Scientific Part Number: 054648-500MG , MDL Number: MFCD00058321

Catalog Number: (89152-148)

Supplier: Enzo Life Sciences

Description: PKC inhibitor

Supplier: Thermo Scientific Chemicals

Description: Inhibitor of protein kinase C and induces apoptosis in cancer cells

SDS Certificates

Supplier: TCI America

Description: CAS Number: 54965-24-1
MDL Number: MFCD00058321
Molecular Formula: C26H29NO
Molecular Weight: 563.65
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Melting point (°C): 142
Storage Temperature: 0-10°C

SDS Certificates

Catalog Number: (77993-777)

Supplier: LGC Standards

Description: TRC Tamoxifen-d5

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Catalog Number: (77986-844)

Supplier: LGC Standards

Description: TRC (E/Z)-4-Hydroxy Tamoxifen

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Supplier: Thermo Scientific Chemicals

Description: Inhibitor of protein kinase C and induces apoptosis in cancer cells

SDS Certificates

Supplier: LGC Standards

Description: Organic Standard, Tamoxifen

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Supplier: MP Biomedicals

Description: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Catalog Number: (77986-847)

Supplier: LGC Standards

Description: TRC 4’-Hydroxy Tamoxifen (contains up to 10% E isomer)

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Supplier: LGC Standards

Description: TRC (E)-Tamoxifen

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Catalog Number: (77981-913)

Supplier: LGC Standards

Description: TRC N-Desmethyl-4’-hydroxy Tamoxifen

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Supplier: Enzo Life Sciences

Description: Tamoxifen metabolite

Catalog Number: (77986-850)

Supplier: LGC Standards

Description: TRC (E)-4-Hydroxy Tamoxifen-d5

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