You Searched For: Boc-L-Lys-MCA


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Supplier: Bachem Americas
Description: Sequence: Boc-Lys(Tfa)-AMC

Catalog Number: (I-1570.0050BA)
Supplier: Bachem Americas
Description: Sequence: Boc-Leu-Lys-Arg-AMC


Supplier: Bachem Americas
Description: Sequence: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂

Supplier: Bachem Americas
Description: Sequence: Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH₂
Synonym(s): Mca-(Asn⁶⁷⁰,Leu⁶⁷¹)-APP₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide

Catalog Number: (M-2455.0001BA)
Supplier: Bachem Americas
Description: FRET substrate for cathepsin D and E.


Supplier: Bachem Americas
Description: Substrate V, Mca-RPPGFSAFK(Dnp), is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1) a membrane-bound zinc metallopeptidase that is related to neprilysin in amino acid sequence. The kcat/Km value for the hydrolysis by ECE-1 was 1.9 x 10⁷ M⁻¹s⁻¹ and 1.7 x 10⁶ M⁻¹s⁻¹ for the hydrolysis by neprilysin. This FRET substrate was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2. Mca-RPPGFSAFK(Dnp) has also found use as substrate for insulin-degrading enzyme (IDE) and ACE2.

Catalog Number: (M-2195.0001BA)
Supplier: Bachem Americas
Description: Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.


Catalog Number: (M-2420.0001BA)
Supplier: Bachem Americas
Description: Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF.


Catalog Number: (M-2485.0001BA)
Supplier: Bachem Americas
Description: Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP. The kinetic parameters of Mca-SEVNLDAEFK(Dnp) amide at pH 4.5 are Km = 4.5 µM and kcat = 0.25 min⁻¹.


Supplier: Bachem Americas
Description: Sequence: Boc-Leu-Gly-Arg-AMC

Catalog Number: (102996-800)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.
Sequence:Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
MW:1675.9 Da
% peak area by HPLC:95
Storage condition:-20° C


Supplier: Bachem Americas
Description: FRET substrate for angiotensin-converting enzyme 2 (ACE2). Mca-APK(Dnp)-OH is used for monitoring the activity of the enzyme in plasma, urine, heart, and lungs.

Supplier: Bachem Americas
Description: Sequence: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂
Synonym(s): NFF-3

Catalog Number: (I-1545.0050BA)
Supplier: Bachem Americas
Description: Sequence: Boc-Glu(OBzl)-Gly-Arg-AMC · HCl


Catalog Number: (77461-434)
Supplier: AAT BIOQUEST INC
Description: TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2] has much stronger fluoresce upon protease cleavage than the commonly used FRET peptide MCA-HQKLVFFA (K-DNP), a secretase FRET peptide substrate.

New Product


Catalog Number: (10815-692)
Supplier: Thermo Scientific Chemicals
Description: Molecular Formula: C60H74N14O21
Formula Weight: 1327.31
Storage Temperature: -30°C to -10°C
Physical Form: Lyophilized powder
Appearance: White to off-white


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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