Mca-Lys-Pro-Leu-Gly-Leu-Dap -Ala-Arg-Nh₂

Supplier: BACHEM AMERICAS INC

Synonyms: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂

4028885.0001 4028885.0005
M-2350.0001BAEA 457.5 USD
M-2350.0001BA M-2350.0005BA
Mca-Lys-Pro-Leu-Gly-Leu-Dap -Ala-Arg-Nh₂
Mca-Lys-Pro-Leu-Gly-Leu-Dap -Ala-Arg-Nh₂

Sequence: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂


The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH₂ (M-1895) with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to M-1895, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate M-2350, Mca-KPLGL-Dpa-AR-NH₂ for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.

Formula: C₅₅H₈₀N₁₆O₁₆
MW: 1221.341 g/mol
Storage Temperature: Freezer
MDL Number: MFCD07368601
CAS Number: 720710-69-0

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