Mca-Lys-Pro-Leu-Gly-Leu-Dap -Ala-Arg-Nh₂
Supplier: BACHEM AMERICAS INC
Synonyms:
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
Sequence: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH₂ (M-1895) with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to M-1895, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate M-2350, Mca-KPLGL-Dpa-AR-NH₂ for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.
Formula:
C₅₅H₈₀N₁₆O₁₆ MW: 1221.341 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD07368601 CAS Number: 720710-69-0 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...