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Product Image-JT7578-R

J.T.Baker® BAKERBOND® C18, Prep LC Packing, Non-Endcapped

Catalog Number: (JT7578-R)
Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: BAKERBOND®, BAKERBOND® C18 Prep LC Packing, Non-Endcapped, Spherical, 50 µm, 120 Å

SDS Certificates


Image Unavailable-77439-574

Anti-IRS1 Rabbit Polyclonal Antibody

Catalog Number: (77439-574)
Supplier: Bioss
Description: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Image Unavailable-76449-282

VWR® Adhesive Sealing Strips, PP, 1×8

Catalog Number: (76449-282)
Supplier: VWR International
Description: 1x8 adhesive sealing strips are ideal for use with 1x8 strip-well ELISA plates.
Image Unavailable-10355-828

Anti-IRS1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10355-828)
Supplier: Bioss
Description: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Image Unavailable-10355-832

Anti-IRS1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10355-832)
Supplier: Bioss
Description: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Image Unavailable-EM1.08110.0500

Tetrahydrofuran, Uvasol® for spectroscopy, Supelco®

Supplier: MilliporeSigma
Description: Accurate analytic results in UV/VIS and infrared spectroscopy depend on the use of very pure solvents for sample preparation. The Uvasol® solvents range has been specially designed for spectroscopy and other applications requiring solvents of the highest spectral purity. The refinement process allows a greater degree of security in applications and avoids misinterpretation of analytical results caused by traces of UV, IR and fluorescence contamination. Uvasol® solvents offer best UV transmittance. In all specifications the minimum transmittance for 5 typical wavelengths are identified. Furthermore the transmittance is specified in accordance with Reag. Ph Eur and ACS.

SDS Certificates

Product Image-76015-284

Semi-Micro Raised-Bottom Black Cuvette with PTFE Cover (Lightpaths: 10×1 to 10×5 mm), Type 9BM

Supplier: FIREFLYSCI, INC.
Description: Semi-micro spectrophotometer cuvette with PTFE cover, made with black quartz.

Product Image-AG9910024500

Barrel Nebulizers, Impact Beads and Supplies for Mark V, VI and 7 Spray Chambers

Catalog Number: (AG9910024500)
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Description: Barrel nebulizers for Agilent AA instruments that feature the Mark V or Mark VI atomization system. The adjustable impact bead in the flame atomization system helps aerosol formation.
Image Unavailable-10355-836

Anti-IRS1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10355-836)
Supplier: Bioss
Description: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Image Unavailable-10355-826

Anti-IRS1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10355-826)
Supplier: Bioss
Description: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
Image Unavailable-EM1.06002.0500

Methanol, Uvasol® for spectroscopy, Supelco®

Supplier: MilliporeSigma
Description: Accurate analytic results in UV/VIS and infrared spectroscopy depend on the use of very pure solvents for sample preparation. The Uvasol® solvents range has been specially designed for spectroscopy and other applications requiring solvents of the highest spectral purity. The refinement process allows a greater degree of security in applications and avoids misinterpretation of analytical results caused by traces of UV, IR and fluorescence contamination. Uvasol® solvents offer best UV transmittance. In all specifications the minimum transmittance for 5 typical wavelengths are identified. Furthermore the transmittance is specified in accordance with Reag. Ph Eur and ACS.

SDS Certificates Environmentally Preferable

Product Image-76015-178

Macro Open Bottom Fluorescence Flow Through Cells, FireflySci

Supplier: FIREFLYSCI, INC.
Description: High-quality macro open bottom fluorescence flow through are of a great value.

Product Image-10107-956

Anti-PCBP1 Rabbit Polyclonal Antibody

Catalog Number: (10107-956)
Supplier: Prosci
Description: PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Product Image-10802-932

Anti-IgG Mouse Monoclonal Antibody (DyLight® 800) [clone: eB182]

Catalog Number: (10802-932)
Supplier: Rockland Immunochemical
Description: Rabbit IgG TrueBlot® is a unique DyLight™ 800 conjugated anti-rabbit IgG immunoblotting (second step) reagent. Rabbit IgG TrueBlot® enables detection of immunoblotted target protein bands, without hindrance by interfering immunoprecipitating immunoglobulin heavy and light chains. It is easy to generate publication-quality IP/Fluorescent Western Blot data with Rabbit IgG TrueBlot®, simply substitute the conventional DL800 anti-rabbit IgG blotting reagent with Fluorescent Rabbit TrueBlot® Antibody DyLight™ 800 and follow the prescribed protocol for sample preparation and immunoblotting. Ideal for Li Cor Odyssey imaging as well as other IR and near IR imaging systems.

Rabbit IgG TrueBlot® is ideal for use in protocols involving immunoblotting of immunoprecipitated proteins. TrueBlot preferentially detects the non-reduced form of rabbit IgG over the reduced, SDS-denatured form of IgG. When the immunoprecipitate is fully reduced immediately prior to SDS-gel electrophoresis, reactivity of Rabbit IgG TrueBlot® with the 55 kDa heavy chains and the 23 kDa light chains of the immunoprecipitating antibody is minimized thereby eliminating interference by the heavy and light chains of the immunoprecipitating antibody in IP/Western blotting applications. Applications include studies examining post-translational modification (e.g., phosphorylation or acetylation) or protein-protein interactions. Fluorescent Rabbit TrueBlot® Antibody DyLight™ 800 may also be used for detection in immunoassays that do not employ immunoprecipitation.
Product Image-76015-130

Type 1 Macro Cuvettes with PTFE Cover, FireFlySci

Supplier: FIREFLYSCI, INC.
Description: The Firefly Type 1 standard 10 mm cell spectroscopy comes in many various lightpaths and materials to fit the exact needs.

Product Image-76016-178

Flow Through Cells with Side Tubes, FireflySci

Supplier: FIREFLYSCI, INC.
Description: High-quality flow through cells in a variety of material types and are a great value.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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