You Searched For: AMP+PNP


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Catalog Number: (10395-406)
Supplier: Bioss
Description: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.


Catalog Number: (10430-272)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Catalog Number: (10430-260)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Supplier: Matrix Scientific
Description: 4-(Aminomethyl)piperidine ≥97%

Supplier: Molecular Devices
Description: CatchPoint® Cyclic-AMP Fluorescent Assay Kit: Cell signaling via G protein-coupled receptors (GPCRs) can be assessed by monitoring the downstream effectors calcium or cyclic AMP (<B>cAMP</B>).

Supplier: Ambeed
Description: 4-(Aminomethyl)piperidine 96%

Catalog Number: (76101-630)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism.


Supplier: Alere
Description: Rapid Drug Screen for the simultaneous, qualitative detection of single or multiple drug metabolites in human urine

SDS

Supplier: Alere
Description: Rapid Drug Screen for the simultaneous, qualitative detection of single or multiple drug metabolites in human urine

Supplier: StatLab
Description: <p>Slides for routine H&E or special stain applications.</p>

New Product

Supplier: Adipogen
Description: Mitochondria-derived peptide (MDP). Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound.

Catalog Number: (89151-574)
Supplier: Enzo Life Sciences
Description: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).


Catalog Number: (10336-552)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism.


Catalog Number: (10336-556)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism.


Supplier: Enzo Life Sciences
Description: Cell-permeable, potent and AMP-competitive inhibitor of glycogen phosphorylase.

Catalog Number: (TCA2112-100MG)
Supplier: TCI America
Description: CAS Number: 37839-81-9
MDL Number: MFCD00069736
Molecular Formula: C10H12N5O6P
Molecular Weight: 351.19
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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