You Searched For: ACY-1215

Supplier: ALADDIN SCIENTIFIC CORPORATION

Description: Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.

New Product

Supplier: Ambeed

Description: ACY-1215 98+%

Supplier: LGC STANDARDS

Description: Carbon Steel, Rephosphorized and Resulfurized, AISI 1215, G12150, Ø38x3mm, ARMI | MBH, LGC Standards

New Product

Supplier: Ambeed

Description: (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone), Purity: 98+%, CAS Number: 1415800-43-9, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 1mg

Catalog Number: (77615-776)

Supplier: Ambeed

Description: (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-3-Amino-2-hydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one ≥98%

New Product

Supplier: Matrix Scientific

Description: Matrix Scientific Part Number: 009194-5G , MDL Number: MFCD00005676

Supplier: Bachem Americas

Description: Anticoagulant and antithrombotic peptides. Please see also the product family 'Hirudin Fragments and Analogs', the inhibitors N-1065, N-1215, N-1260, N-1565, and N-1970, and the anticoagulant anisindione, Q-1085.

Catalog Number: (101918-862)

Supplier: Matrix Scientific

Description: Matrix Scientific Part Number: 059676-500MG , MDL Number: MFCD00508667

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00001593 Beilstein Registry No.: 747939 Fieser: 1,215 14,126 15,125 16,120 18,130 19,121 20,137 21,164

SDS Certificates

Supplier: Bachem Americas

Description: Sequence: H-Gly-Arg-AMC

Supplier: Bachem Americas

Description: Sequence: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine.

Supplier: TLC Standards

Description: Pharmaceutical Standards, Clobutinol HCl (Mixture of Diastereomers)

New Product

Catalog Number: (10355-868)

Supplier: Bioss

Description: HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.

Supplier: Ambeed

Description: N1,N2-Bis(4-(pyridin-2-yl)benzyl)ethane-1,2-diamine, Purity: 98%, CAS Number: 1507370-20-8, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8C, Size: 5MG

Supplier: Bachem Americas

Description: Anticoagulant and antithrombotic peptides. Please see also the product family 'Hirudin Fragments and Analogs', the inhibitors N-1065, N-1215, N-1260, N-1565, and N-1970, and the anticoagulant anisindione, Q-1085.

Catalog Number: (76083-700)

Supplier: Bioss

Description: HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.