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Supplier: AAT BIOQUEST INC
Description: 2',3'-cGAMP or cGAMP (Cyclic guanosine monophosphate" adenosine monophosphate) is produced in mammalian cells by cGAS (cGAMP synthase) from ATP and GTP upon cytosolic DNA stimulation.

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Supplier: Cayman Chemical Company
Description: 3 3-cGAMP (sodium salt), Purity: >/=98%, Appearance: Crystalline solid, Second messenger, Synonyms: 3',3'-Cyclic GMP-AMP, Adenosine-Guanosine 3',3'-cyclic monophosphate, Adenylyl-(3'?5')-3'-guanylic acid, cyclic nucleotide, disodium salt, c-GpAp, Size: 500ug

Supplier: Cayman Chemical Company
Description: 2 3 cGAMP (sodium salt), Purity: >/=98%, Appearance: solid, A second messenger and inducer of IFN-B production, Synonyms: Adenylyl-(3'?5')-2'-guanylic acid, cyclic nucleotide, disodium salt, Guanosine-Adenosine 2',3'-cyclic monophosphate, Size: 500ug

Supplier: Adipogen
Description: Potent STING ligand. Second messenger in human and mouse cells that triggers interferon production in response to cytosolic DNA. Binding to STING leads to activation of IRF3 (IFN regulatory factor 3) and the induction of interferon-beta. First cyclic nucleotide in metazoa. Plays a role in bacterial chemotaxis and colonization.

Catalog Number: (76293-162)
Supplier: Cayman Chemical Company
Description: STING A162 variant (human recombinant) contains amino acids 138-379 of the wild-type variant (R232) with an alanine substituted for serine at position 162. Stimulator of interferon genes (STING) is a component of the innate immune response that binds to cyclic dinucleotides, which are bacterial second messengers, leading to activation of NF-κB and transcription of immunomodulatory genes, including type I interferon (IFN). The R232 variant of STING is the most common variant in the human population, found at a frequency of 57.9% in the 1000 Genome Project. The SNP variant H232 is found at a 13.7% frequency. The S162A point mutation is located in the cyclic dinucleotide binding site of the human STING variants R232 and H232 and allows human STING to bind to DMXAA, a compound previously known to bind mouse, but not human, STING. When STING S162A is bound to DMXAA, it adopts the closed conformation, similar to the conformation it has when bound to the second messenger 2’3’-cGAMP (Item No. 19887), and activates the IFN pathway similarly to mouse STING.


Catalog Number: (77461-748)
Supplier: AAT BIOQUEST INC
Description: 2’,3’-cGAMP succinimidyl ester is an excellent reagent to covalently conjugate 2’,3’-cGAMP to biological targets, such as proteins, peptides, and nucleic acids.

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Supplier: AAT BIOQUEST INC
Description: 2',3'-cGAMP or cGAMP (Cyclic guanosine monophosphate"adenosine monophosphate) is produced in mammalian cells by cGAS (cGAMP synthase) from ATP and GTP upon cytosolic DNA stimulation.

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Catalog Number: (77461-750)
Supplier: AAT BIOQUEST INC
Description: 2’,3’-cGAMP maleimide is an excellent reagent to covalently conjugate 2’,3’-cGAMP to thiol containing-or thiol-modified biological targets, such as proteins, peptides, and nucleic acids.

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Catalog Number: (77461-738)
Supplier: AAT BIOQUEST INC
Description: iFluor® 488-labeled cGAMP provides an excellent fluorescent probe for developing fluorescence-based assays and tests for detecting cGAMP or monitoring its activity.

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Catalog Number: (77461-744)
Supplier: AAT BIOQUEST INC
Description: DBCO (dibenzocyclooctyne) click chemistry is a bioconjugation technique used to covalently attach molecules to biological targets, such as proteins, peptides, and nucleic acids.

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Catalog Number: (77461-746)
Supplier: AAT BIOQUEST INC
Description: 2’,3’-cGAMP azide is an excellent reagent to conjugate 2’,3’-cGAMP to alkyne-modified biological targets, such as proteins, peptides, and nucleic acids.

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Supplier: Cayman Chemical Company
Description: 2 2-cGAMP, Purity: >/=98%, Cas number: 1465774-27-9, Molecular Formula: C20H24N10O13P2, Molecular Weight: 674.4 g/mol, Synonyms: 2,2 -Cyclic GMP-AMP, Adenosine-Guanosine 2,2 -cyclic monophosphate, adenylyl-(2 ? 5 )-2 -guanylic acid, Size: 500ug

Catalog Number: (77461-740)
Supplier: AAT BIOQUEST INC
Description: iFluor® 647-labeled cGAMP provides an excellent fluorescent probe for developing fluorescence-based assays and tests for detecting cGAMP or monitoring its activity.

New Product


Catalog Number: (76485-124)
Supplier: AAT BIOQUEST INC
Description: 2',3'-cGAMP or cGAMP (Cyclic guanosine monophosphate "adenosine monophosphate) is produced in mammalian cells by cGAS (cGAMP synthase) from ATP and GTP upon cytosolic DNA stimulation.

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Catalog Number: (BDH152803U)
Supplier: VWR International
Description: Ion pairing reagent.

Catalog Number: (76292-890)
Supplier: Cayman Chemical Company
Description: For the quantification of 2’3’-cGAMP in cell lysates.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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