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You Searched For: (S)-(+)-Camptothecin


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(S)-(+)-Camptothecin

Supplier: APOLLO SCIENTIFIC
Description: (S)-(+)-Camptothecin

New Product

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(S)-(+)-Camptothecin ≥98% (by HPLC)

Supplier: Adipogen
Description: Potent anticancer compound. Cell permeable potent DNA topoisomerase I (Topo I) complex inhibitor. Potent apoptosis inducer. Binds reversibly to the DNA topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. The enzyme complex is ubiquinated and destroyed by the 26S proteasome, consequently depleting cellular topoisomerase I. Prevents DNA re-ligation and therefore causes DNA damage which results in apoptosis. Inhibits mitochondrial topoisomerase I (mtTop1). Blocks the cell cycle at low dose and induces apoptosis in a large number of normal and tumor cell lines by cell cycle-dependent and cell cycle-independent processes. Antiprotozoal and antimalarial compound. Inhibitor of HIV replication and of other viruses. Suppresses nitric oxide (NO) biosynthesis. Shown to suppress TNF-alpha-induced expression of the inflammasome and cyclooxygenase 2 (COX-2).

Product Image-89148-940

(S)-(+)-Camptothecin ≥98%

Supplier: Enzo Life Sciences
Description: Potent antitumor agent

Product Image-82021-598

(S)-(+)-Camptothecin 2 mM

Catalog Number: (82021-598)
Supplier: G-Biosciences
Description: Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).
Image Unavailable-TCC1495-100MG

(S)-(+)-Camptothecin ≥97.0% (by HPLC)

Supplier: TCI America
Description: CAS Number: 7689-03-4
MDL Number: MFCD00081076
Molecular Formula: C20H16N2O4
Molecular Weight: 348.36
Purity/Analysis Method: >97.0% (HPLC)
Form: Crystal
Specific rotation [a]20/D: 40 deg (C=0.4, CHCl3:MeOH=8:2)

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(S)-(+)-Camptothecin ≥98%

Supplier: Ambeed
Description: (S)-(+)-Camptothecin ≥98%

New Product

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(S)-(+)-Camptothecin ≥90%

Supplier: Thermo Scientific Chemicals
Description: Cytotoxic antitumor agent that inhibits topoisomerase I

SDS Certificates

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(S)-(+)-Camptothecin ≥97%, pale yellow solid

Supplier: MP Biomedicals
Description: (S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.

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(S)-(+)-Camptothecin ≥95%

Supplier: Matrix Scientific
Description: MF=C20H16N2O4 MW=348.36 CAS=7689-03-4 MDL=MFCD00081076 1G

Image Unavailable-80055-998

(S)-(+)-Camptothecin (from Camptotheca acuminata), Sigma-Aldrich®

Catalog Number: (80055-998)
Supplier: MilliporeSigma
Description: A DNA topoisomerase I inhibitor

SDS Certificates


Product Image-82021-608

Apoptosis Inducers, G-Biosciences

Catalog Number: (82021-608)
Supplier: G-Biosciences
Description: Apoptosis inducers are used for induction of apoptosis in cultured cells. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, doxorubicin and etoposide.
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9-Aminocamptothecin ≥95%

Catalog Number: (ALA139433-5MG)
Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: 9-Aminocamptothecin is an active derivative of camptothecin, which belongs to the general group of chemotherapy drugs called topoisomerase inhibitors. 9-Aminocamptothecin is an inhibitor of Topo I.An active derivative of camptothecin and topoisomerase inhibitor

New Product


Product Image-TS45909-1000

7-Ethyl-10-hydroxycamptothecin 98%

Supplier: Thermo Scientific Chemicals
Description: 7-Ethyl-10-hydroxycamptothecin 98%

Product Image-89161-590

3,4-Dichloroisocoumarin ≥98% (by elemental analysis)

Catalog Number: (89161-590)
Supplier: Enzo Life Sciences
Description: A potent irreversible mechanism based serine protease inhibitor. Inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase and proteinase 3. Inhibits activation of neutral sphingomyelinase and apoptosis triggered by daunorubicin as well as camptothecin-induced apoptosis in HL-60 cells. Inhibits migration of eosinophils through basement membrane components in vitro.
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Apoptosis inducer set, Enzo Life Sciences

Catalog Number: (89155-990)
Supplier: Enzo Life Sciences
Description: The set contains 5 ready-to-use reagents that induce apoptosis through different mechanisms. Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.
Image Unavailable-TCA2063-10MG

9-Aminocamptothecin ≥95.0% (by HPLC)

Catalog Number: (TCA2063-10MG)
Supplier: TCI America
Description: CAS Number: 91421-43-1
MDL Number: MFCD00909855
Molecular Formula: C20H17N3O4
Molecular Weight: 363.37
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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