You Searched For: (E\/Z)-4-Hydroxytamoxifen


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Supplier: Enzo Life Sciences
Description: Tamoxifen metabolite

Supplier: Ambeed
Description: (Z)-4-Hydroxytamoxifen 99%

New Product

Supplier: Ambeed
Description: 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol, Purity: 98%, CAS Number: 68392-35-8, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G

Supplier: MP Biomedicals
Description: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Catalog Number: (220181-980)
Supplier: Sigma Aldrich
Description: 4-HYDROXYTAMOXIFEN

Blocked

Catalog Number: (102656-742)
Supplier: American Radiolabeled Chemicals
Description: 4 HYDROXYTAMOXIFEN M 250 UCI


Catalog Number: (76270-964)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: 4-HYDROXYTAMOXIFEN >/=98% 1115-70-4 50MG


Catalog Number: (220181-366)
Supplier: Sigma Aldrich
Description: 4-HYDROXYTAMOXIFEN

Blocked

Catalog Number: (TS469501000)
Supplier: Thermo Scientific Chemicals
Description: (Z)-4-HYDROXYTAMOXIFEN 99% 100MG

New Product


Catalog Number: (76271-098)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: (Z)-4-HYDROXYTAMOXIFEN PURITY>/=98% 25MG


Catalog Number: (102663-016)
Supplier: American Radiolabeled Chemicals
Description: 4 HYDROXYTAMOXIFEN M 5 MG


Catalog Number: (102642-480)
Supplier: Chem Impex International
Description: 4-HYDROXYTAMOXIFEN 25MG


Catalog Number: (102663-018)
Supplier: American Radiolabeled Chemicals
Description: 4 HYDROXYTAMOXIFEN M 25 MG


Catalog Number: (220181-979)
Supplier: Sigma Aldrich
Description: 4-HYDROXYTAMOXIFEN

Blocked

Catalog Number: (102624-084)
Supplier: Chem Impex International
Description: 4-HYDROXYTAMOXIFEN 5MG


Catalog Number: (102867-936)
Supplier: R&D Systems
Description: (Z)-4-HYDROXYTAMOXIFEN (50 MG)


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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