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Catalog Number: (103006-690)

Supplier: Anaspec Inc

Description: Caloxin 1b1 is obtained by screening for binding to extracellular domain 1 of PMCA4, which inhibited PMCA extracellularly, selectively, and had a higher affinity for PMCA4 than PMCA1. Because caloxin 1b1 had been selected to bind to an extracellular domain of PMCA, it could be added directly to cells and tissues to examine its effects on smooth muscle and endothelium.
Sequence:TAWSEVLHLLSRGGG
MW:1582.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103011-036)

Supplier: Anaspec Inc

Description: This product is a very useful building block for preparing red fluorescent biomolecules. We have also proven that it is a good transglutaminase substrate.

Catalog Number: (103010-016)

Supplier: Anaspec Inc

Description: The peptide YFLLRNP is an antagonist to thrombin and SFLLRNP (thrombin receptor agonist peptide) in human platelets. YFLLRNP can induce partial activation of human platelets, visible by shape change; but it is unable to fully activate the platelets.
Sequence: YFLLRNP - OH
MW: 922.1 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Catalog Number: (103009-844)

Supplier: Anaspec Inc

Description: This peptide is Histone 3 amino acid residues 21 to 44. It is mono-methylated at Lys27 and Lys36 with a C-terminal G linker followed by a biotinylated lysine. Histone methylation plays an important role in the regulation of chromatin structure and function. Related Peptides: [Lys(Ac)27, Lys(Me1)36]-Histone H3 (21-44)-GK(Biotin), H3K27(Ac)K36(Me1), biotin-labeled, Cat# 65444 [Lys(Ac)27, Lys(Me2)36]-Histone H3 (21-44)-GK(Biotin), H3K27(Ac)K36(Me2), biotin-labeled, Cat# 65445
Sequence:ATKAAR-K(Me1)-SAPATGGV-K(Me1)-KPHRYRPG-GK(Biotin)
MW:2946.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (102996-380)

Supplier: Anaspec Inc

Description: This GLP-1 (7-36) amide, is labeled with biotin at the peptide N-terminus. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.
Sequence: Biotin-HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
MW: 3524 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (103006-570)

Supplier: Anaspec Inc

Description: This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 2Abz/Dnp FRET pair for quantitation of complement enzyme activity.
Sequence:2Abz-SLGRKIQIK(Dnp)-NH2
MW:1326.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103007-278)

Supplier: Anaspec Inc

Description: This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1 – 20) induces T-cell–mediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.
Sequence:GPTHLFQPSLVLDMAKVLLD
MW:2194.6 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Description: 6-TAMRA is the other purified single isomer of 5(6)-TAMRA. It is predominantly used for nucleotide labeling.

Catalog Number: (102999-778)

Supplier: Anaspec Inc

Description: This is Oxytocin (OT) N-terminally labeled with Biotin. OT is a 9-amino acid peptide that is synthesized primarily in the hypothalamic neurons, specifically the magnocellular oxytocin neurons in the supraoptic and paraventricular nuclei and is secreted by the posterior pituitary gland. It is also secreted from other tissues, such as the ovaries and testes. Circulating OT is important during parturition and lactation. In the pregnant uterus, oxytocin and the oxytocin receptor play a major part for uterine contractility and the induction of labor. OT is also involved in complex social behaviors such as affiliation, sexual behavior, social recognition, stress buffering, aggression, and trust.
Sequence: Biotin-CYIQNCPLG-NH2 (Disulfide bridge: 1-6)
MW: 1234.5 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (103009-170)

Supplier: Anaspec Inc

Description: This peptide is histone H3 (21-44) with deimination at Arg26, converting it to Cit (citrulline). It is biotinylated through a C-terminal GGK linker. Deimination by peptidyl arginine deiminase 4 (PADI4) blocks methylation by the CARM1 methyltransferase and inhibits transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ATKAA-Cit-KSAPATGGVKKPHRYRPG-GGK(Biotin)
MW:2975.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103002-742)

Supplier: Anaspec Inc

Description: The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.
Sequence:CNGRCG (Disulfide bridge: 1-5)
MW:606.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103007-290)

Supplier: Anaspec Inc

Description: This renin FRET peptide is a specific substrate for rat renin. In the FRET peptide, the fluorescence of 5-FAM is quenched by QXL® 520. Upon cleavage into two separate fragments by rat renin, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission = 490/520 nm. The SensoLyte® 520 Renin Assay Kit (cat # 72040) contains the human renin FRET substrate.
MW: 2000 - 2200 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

Catalog Number: (102998-432)

Supplier: Anaspec Inc

Description: This ACTH (18-39) fragment is known as the Corticotropin-like Intermediate Lobe Peptide. It stimulates insulin secretion as well as amylase and protein secretion in a dose-dependent manner similar to those of secretin and carbamylcholine.
Sequence: RPVKVYPNGAEDESAEAFPLEF
MW: 2465.7 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Catalog Number: (103007-700)

Supplier: Anaspec Inc

Description: ClearPoint™ beta-Amyloid (1-42) is a heavy-isotope labeled peptide. All the Arginine and Lysines have universally labeled 13C and 15N.
Sequence: DAEF-R*-HDSGYEVHHQ-K*-LVFFAEDVGSN-K*-GAIIGLMVGGVVIA [R*=R(U-13C6, U-15N4) & K*=K(U-13C6, U-15N2)]
Molecular Weight: 4540.1 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: (102997-266)

Supplier: Anaspec Inc

Description: This peptide is beta-amyloid (1-40) N-terminally truncated. It was shown that supplementing the media with N-terminally truncated Abeta (2-40) and (2-42) induce the phagocytosis of polystyrene particles by primary human monocytes. N-terminally truncated Aβ(x–42) induced the phagocytosis of PSPs significantly more effectively than did Aβ(x–40).
Sequence: AEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Molecular Weight: 4214.8 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: (103010-740)

Supplier: Anaspec Inc

Description: Reference standard for measuring fluorescence quantum yield.