You Searched For: Tamoxifen+citrate

Catalog Number: (80057-564)

Supplier: MilliporeSigma

Description: Tamoxifen Citrate is a potent, synthetic, anti-estrogen

Certificates

Supplier: Thermo Scientific Chemicals

Description: Tamoxifen citrate 98%

Catalog Number: (89152-148)

Supplier: Enzo Life Sciences

Description: PKC inhibitor

Catalog Number: (101907-994)

Supplier: Matrix Scientific

Description: Matrix Scientific Part Number: 054648-500MG , MDL Number: MFCD00058321

Supplier: Thermo Scientific Chemicals

Description: Inhibitor of protein kinase C and induces apoptosis in cancer cells

SDS Certificates

Supplier: TCI America

Description: CAS Number: 54965-24-1
MDL Number: MFCD00058321
Molecular Formula: C26H29NO
Molecular Weight: 563.65
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Melting point (°C): 142
Storage Temperature: 0-10°C

SDS Certificates

Supplier: Thermo Scientific Chemicals

Description: Inhibitor of protein kinase C and induces apoptosis in cancer cells

SDS Certificates

Supplier: LGC Standards

Description: Organic Standard, Tamoxifen

New Product

Supplier: MP Biomedicals

Description: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Supplier: Enzo Life Sciences

Description: Tamoxifen metabolite

Supplier: TLC Standards

Description: Pharmaceutical Standards, 4-Hydroxy Tamoxifen-d5 (Mixture of Z and E Isomers)

Supplier: TLC Standards

Description: Pharmaceutical Standards, N-Nitroso-N-Desmethyl Tamoxifen

Catalog Number: (77694-556)

Supplier: LGC Standards

Description: (Z)-4-Hydroxy Tamoxifen, TRC, LGC Standards

New Product

Catalog Number: (77748-065)

Supplier: Ambeed

Description: Endoxifen ≥97%

New Product

Supplier: Ambeed

Description: (Z)-4-Hydroxytamoxifen 99%

New Product

Supplier: Biotium

Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.