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Supplier: Enzo Life Sciences
Description: Akt inhibitor

Catalog Number: (76082-700)
Supplier: Bioss
Description: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.


Catalog Number: (89319-468)
Supplier: Genetex
Description: Rabbit polyclonal antibody to INPP1 (inositol polyphosphate-1-phosphatase)


Catalog Number: (89354-044)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to IPMK (inositol polyphosphate multikinase)


Catalog Number: (89355-196)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to IP6K2 (inositol hexakisphosphate kinase 2)


Catalog Number: (89354-022)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to INPP5A (inositol polyphosphate-5-phosphatase, 40kDa)


Catalog Number: (89357-076)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to INPP5B (inositol polyphosphate-5-phosphatase, 75kDa)


Catalog Number: (10279-802)
Supplier: Bioss
Description: Inositol polyphosphate multikinase (IPMK) belongs to the inositol phosphokinase (IPK) family and is characterized as having a broad substrate specificity. However, IPMK displays a preference for inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4). IPMK is ubiquitously expressed with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon. IPMK is localized to the nucleus, where it may play a role in the regulation of calcium release from intracellular stores and has been implicated as a drug target for cancer therapies. The gene encoding IPMK maps to human chromosome 10, which contains over 800 genes. Notably, disorders linked to genes on chromosome 10 include Cowden syndrome, Cockayne syndrome and Tetrahydrobiopterin deficiency.


Supplier: TCI America
Description: Benzyl N,N,N',N'-tetraisopropylphosphorodiamidite [B5997] is used in the synthesis of phosphodiesters and phosphorylation of inositols and nucleosides.

New Product

Catalog Number: (95022-014)
Supplier: HiMedia
Description: For the selective isolation of <i>Plesiomonas shigelloides</i> and <i>Aeromonas species</i> from feces and foodstuffs.

Catalog Number: (IC091642954)
Supplier: MP Biomedicals
Description: Dulbecco's Modification of Eagle's Medium 1X with 4.5 g/l glucose, without L-glutamine, i-inositol is ideally suited for supporting and maintaining a vast range of mammalian cell types.


Catalog Number: (89350-276)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to INPP5F (inositol polyphosphate-5-phosphatase F)


Catalog Number: (10448-492)
Supplier: Bioss
Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.


Catalog Number: (89355-226)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to ITPK1 (inositol 1,3,4-triphosphate 5/6 kinase)


Supplier: Ambeed
Description: D-Pinitol 97%

Catalog Number: (76083-960)
Supplier: Bioss
Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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