You Searched For: SKI-II


16,895  results were found

SearchResultCount:"16895"

Sort Results

List View Easy View

Rate These Search Results

Catalog Number: (102151-074)
Supplier: Novus Biologicals
Description: SKI Overexpression Lysate (Adult Normal)


Catalog Number: (76100-734)
Supplier: Bioss
Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.


Catalog Number: (89329-632)
Supplier: Genetex
Description: Rabbit polyclonal antibody to Ski


Catalog Number: (10070-980)
Supplier: Prosci
Description: The ski oncogene family (ski and sno) encodes transcriptional regulators that can affect oncogenic transformation and cellular differenti-ation. ski and sno function as co-activators or co-repressors, modulating transcription by inter-acting with transcription factor complexes. ski interacts with members of the Nuclear Factor I (NFI) family, the retinoic acid receptor, and the nuclear hormone co-regulators NCoR and NCoA62/skip.


Catalog Number: (10749-374)
Supplier: Prosci
Description: Ski Antibody: TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.


Catalog Number: (75931-956)
Supplier: Rockland Immunochemical
Description: SKI3 is a component of the SKI complex which is composed of SKI2, SKI3 and SKI8. The SKI complex interacts with SKI7, making the link between the SKI complex and the exosome in order to perform mRNA degradation. Anti-SKI3 Antibody is ideal for research in Gene Expression.


Catalog Number: (10744-324)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against recombinant v-SKI.


Catalog Number: (76100-736)
Supplier: Bioss
Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.


Catalog Number: (10105-186)
Supplier: Prosci
Description: SKIL belongs to the SKI family and may have regulatory role in cell division or differentiation in response to extracellular signals.


Catalog Number: (102211-396)
Supplier: Novus Biologicals
Description: SKI Peptide. Tested Applications: Blocking/Neutralizing. Tested Reactivity: Human.


Catalog Number: (75931-960)
Supplier: Rockland Immunochemical
Description: TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumor genesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to the Smad proteins activated by TGF-beta and the (BMPs) and preventing their phosphorylation, inhibiting their ability to bind DNA and activate the transcription of downstream genes. SkiP was originally identified as a Ski-interacting protein and was later found to augment the signals induced by TGF-beta but inhibit transcription induced by BMP-2 in C2C12 cells, suggesting that SkiP is a key player in the signaling cascades initiated by TGF-beta and the BMP protein family.


Catalog Number: (77524-052)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968

New Product


Catalog Number: (89415-402)
Supplier: Prosci
Description: Ski Antibody: TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.


Catalog Number: (89415-404)
Supplier: Prosci
Description: SkiP Antibody: TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumorigenesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to the Smad proteins activated by TGF-beta and the (BMPs) and preventing their phosphorylation, inhibiting their ability to bind DNA and activate the transcription of downstream genes. SkiP was originally identified as a Ski-interacting protein and was later found to augment the signals induced by TGF-beta but inhibit transcription induced by BMP-2 in C2C12 cells, suggesting that SkiP is a key player in the signaling cascades inititated by TGF-beta and the BMP protein family.


Catalog Number: (10457-054)
Supplier: Bioss
Description: WDR61 is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (Zhu et al., 2005 [PubMed 16024656]).[supplied by OMIM, Mar 2008].


Catalog Number: (75931-958)
Supplier: Rockland Immunochemical
Description: SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation. Anti-SKI8 Antibody is ideal for research in Gene Expression.


Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
17 - 32 of 16,895
no targeter for Bottom