You Searched For: Ribose(D),+[1-14C]

Catalog Number: (103283-816)

Supplier: Novus Biologicals

Description: The PARP Antibody from Novus Biologicals is a rabbit polyclonal antibody to PARP. This antibody reacts with human. The PARP Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.

Catalog Number: (10105-750)

Supplier: Prosci

Description: The PARP11 gene is part of the poly (ADP-ribose) polymerase family.

Supplier: Tonbo Biosciences

Description: The HB7 antibody is specific for human CD38, a 45 kDa type II transmembrane glycoprotein expressed on thymocytes, plasma cells, and monocytes as well as other non-hematopoietic cells. T and B lymphocyte expression is discontinuous and varies based on differentiation state � present on immature cells, low on intermediate stages, and high on activated mature cells. It is found on most CD34+ cells, but not on pluripotent stem cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.

Catalog Number: (89147-562)

Supplier: Enzo Life Sciences

Description: Water-soluble, potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1).

Catalog Number: (76235-068)

Supplier: Rockland Immunochemical

Description: PARP1 is the primary member of the poly(ADP-ribose) polymerase family, whose function is to signal DNA damage (and to recruit repair proteins) by PARylation. PARP1 is also involved in multiple cell death pathways, including apoptosis, necroptosis, autophagy, and a relatively new pathway termed parthanatos. It has been implicated in a new form of cell death termed parthanatos. PARP1 can also promote tissue survival by shifting the balance of cell death programs between autophagy and necrosis. Clinical studies have shown vulnerability to PARP inhibitors in DNA repair defective cancers. Anti-PARP1 (internal) antibody is useful for researchers interested in cellular processes including DNA damage, transcriptional control, and stem cell identity research.

Catalog Number: (103268-018)

Supplier: Novus Biologicals

Description: The PARP10 Antibody from Novus Biologicals is a rabbit polyclonal antibody to PARP10. This antibody reacts with human. The PARP10 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Catalog Number: (76010-258)

Supplier: Prosci

Description: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).

Catalog Number: (89289-776)

Supplier: Genetex

Description: Rabbit polyclonal antibody to PP14C

Catalog Number: (76235-070)

Supplier: Rockland Immunochemical

Description: PARP1 is the primary member of the poly(ADP-ribose) polymerase family, whose function is to signal DNA damage (and to recruit repair proteins) by PARylation. PARP1 is also involved in multiple cell death pathways, including apoptosis, necroptosis, autophagy, and a relatively new pathway termed parthanatos. It has been implicated in a new form of cell death termed parthanatos. PARP1 can also promote tissue survival by shifting the balance of cell death programs between autophagy and necrosis. Clinical studies have shown vulnerability to PARP inhibitors in DNA repair defective cancers. Anti-PARP1 (internal) antibody is useful for researchers interested in cellular processes including DNA damage, transcriptional control, and stem cell identity research.

Catalog Number: (89147-716)

Supplier: Enzo Life Sciences

Description: Potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor (IC50=450nM). Neuroprotectant.

Catalog Number: (103264-572)

Supplier: Southern Biotechnology

Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.

Catalog Number: (76234-940)

Supplier: Rockland Immunochemical

Description: PARP1 is the primary member of the poly(ADP-ribose) polymerase family, whose function is to signal DNA damage (and to recruit repair proteins) by PARylation. PARP1 is also involved in multiple cell death pathways, including apoptosis, necroptosis, autophagy, and a relatively new pathway termed parthanatos. It has been implicated in a new form of cell death termed parthanatos. PARP1 can also promote tissue survival by shifting the balance of cell death programs between autophagy and necrosis. Clinical studies have shown vulnerability to PARP inhibitors in DNA repair defective cancers. Anti-PARP1 (N-term ZF1) antibody is useful for researchers interested in cellular processes including DNA damage, transcriptional control, and stem cell identity research.

Catalog Number: (76234-938)

Supplier: Rockland Immunochemical

Description: PARP1 is the primary member of the poly(ADP-ribose) polymerase family, whose function is to signal DNA damage (and to recruit repair proteins) by PARylation. PARP1 is also involved in multiple cell death pathways, including apoptosis, necroptosis, autophagy, and a relatively new pathway termed parthanatos. It has been implicated in a new form of cell death termed parthanatos. PARP1 can also promote tissue survival by shifting the balance of cell death programs between autophagy and necrosis. Clinical studies have shown vulnerability to PARP inhibitors in DNA repair defective cancers. Anti-PARP1 (N-term ZF1) antibody is useful for researchers interested in cellular processes including DNA damage, transcriptional control, and stem cell identity research.

Supplier: MP Biomedicals

Description: Uridine is a nucleoside, contains an uracil attached to a ribose ring (known as a ribofuranose) via a β-N1-glycosidic bond. It is an organic compound of the pyrimidine family, that occurs as one of the four bases coding genetic information in the polynucleotide chain of RNA.
Uridine can increase the rate-limiting step of Phosphatidylcholine synthesis in the brain, Phosphatidylcholine is the major structural and functional component of brain cell membranes. Without phosphatidylcholine, brain cells lose their youthful function and suffer the degenerative structural changes associated with aging. Uridine is thought to aid Alzheimer's Disease due to helping with synaptic connections, which appear to be reduced in the state of Alzheimer's.
Physical Appearance: White Powder
UV/Visible Absorbance: λ max (water)= 260 - 263 nm
Solubility: Soluble in 0.1 N HCl (50 mg/mL-clear, colorless solution) and water (50 mg/mL)

Certificates

Catalog Number: (H-2744.1000BA)

Supplier: Bachem Americas

Description: The amylin fragment Ac-ATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH₂ completely reversed the inhibitory effects of IAPP on ¹⁴C-glycogen accumulation in vitro. It proved to be a most effective amylin antagonist with limited ability to block inhibition by CGRP.

Catalog Number: (103264-568)

Supplier: Southern Biotechnology

Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.