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Product Image-77753-096

Rat Recombinant IL-3 B (from E. coli)

Supplier: VWR International
Description: Interleukin 3 beta (IL-3 β) is a cytokine that is produced by activated T cells and mast cells. IL-3 β induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 β also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.

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Product Image-77751-470

Human Recombinant GROWTH HORMONE (from E. coli)

Supplier: VWR International
Description: Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the anterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. In children, GH deficiencies can cause short stature, growth failure, and delayed sexual maturity.

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Product Image-77752-780

Mouse Recombinant RELM G (from E. coli)

Supplier: VWR International
Description: Resistin-like molecule-gamma (RELM-γ) is a member of the RELM family of secreted proteins containing C-terminal cysteines. The RELM family consists of Resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-γ (FIZZ4). RELM-γ is secreted by peripheral blood granulocytes, bone marrow, spleen, intestine, and lung. RELM-γ functions to promote and regulate promyelocytic differentiation, in addition to regulating nutrient-associated insulin sensitivity in the intestinal tract. Rodents secrete all four RELM family members, whereas Resistin and RELM-β are the only RELM family members found in humans.

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Product Image-77752-000

Mouse Recombinant B-NGF (from E. coli)

Supplier: VWR International
Description: Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.

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Product Image-77752-006

Mouse Recombinant B-NGF (from E. coli)

Supplier: VWR International
Description: Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.

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Product Image-77751-430

Human Recombinant B-NGF (from E. coli)

Supplier: VWR International
Description: Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive. 

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Product Image-77750-402

Human Recombinant IGF-II (from E. coli)

Supplier: VWR International
Description: Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

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Product Image-77750-474

Human Recombinant IGF-II (from E. coli)

Supplier: VWR International
Description: Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

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Product Image-77752-518

Mouse Recombinant IL-17E (from E. coli)

Supplier: VWR International
Description: Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17RB receptor to stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine and to induce the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).

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Product Image-77752-404

Mouse Recombinant IL-27/P28 (from E. coli)

Supplier: VWR International
Description: <p>The p28 subunit of interleukin 27 (IL-27), also known as interleukin 30 (IL-30), is a member of the interleukin 12 (IL-12) family of cytokines. p28 is a secreted polypeptide that associates with the Epstein-Barr virus induced gene 3 (EBI3) to form the IL-27 cytokine heterodimer complex.</p>

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Product Image-77752-868

Rat Recombinant IL-6 (from E. coli)

Supplier: VWR International
Description: Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains.

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Product Image-77751-232

Human Recombinant CD40-Ligand (from E. coli)

Supplier: VWR International
Description: <p>CD40-Ligand, or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40-Ligand binds and activates the CD40 receptor on antigen-presenting cells. CD40-Ligand stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion.</p>

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Product Image-77751-244

Human Recombinant CD40-Ligand (from E. coli)

Supplier: VWR International
Description: <p>CD40-Ligand, or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40-Ligand binds and activates the CD40 receptor on antigen-presenting cells. CD40-Ligand stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion.</p>

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Product Image-77751-162

Human Recombinant FLT-3 Ligand (from E. coli)

Supplier: VWR International
Description: <p>Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells.</p>

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Product Image-77753-438

Human/Mouse/Rat Recombinant Activin-A (from E. coli)

Supplier: VWR International
Description: Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion.  Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism.  Activin A is a homodimer comprised of two activin βA chains. Cleavage of the N-terminal propeptide renders the Activin protein biologically active. Human Activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline Activin A proteins.

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Product Image-77752-436

Mouse Recombinant VEGF-120 (from E. coli)

Supplier: VWR International
Description: Vascular endothelial growth factor A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. Mouse VEGF-A has several alternatively spliced isoforms, with one being VEGF-120. VEGF-120 is an angiogenic factor that is expressed throughout endochondral bone development and is important during skeletogenesis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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