You Searched For: 5-Bromoisoquinolin-1(2H)-one

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Biocytin TMR, CF® 640R Dye

Catalog Number: (75784-060)

Supplier: Biotium

Description: CF®640R, A highly photostable far-red dye

SDS

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Mix-n-Stain™ Nanobody Labeling Kits, Biotium

Supplier: Biotium

Description: The simplicity and convenience of Mix-n-Stain™ labeling of nanobodies with fluorescent CF® dyes or biotin.

Anti-Biotin Mouse Monoclonal Antibody (CF405M) [clone: Hyb8]

Supplier: Biotium

Description: This antibody recognizes both the free and protein-conjugated (either soluble or cell bound) form of biotin. This MAb is highly specific to biotin and shows no cross-reaction with other structurally related compounds. It has a very high affinity for biotin and is excellent for use in various amplification techniques. In some applications, localization of biotinylated probes with avidin produces unacceptably high background staining. Anti-biotin antibody may be substituted to decrease this noise.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405M is a blue fluorescent dye (Ex/Em 408/452 nm) with superior brightness and photostability compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Anti-Biotin Mouse Monoclonal Antibody (CF405S) [clone: Hyb8]

Supplier: Biotium

Description: This antibody recognizes both the free and protein-conjugated (either soluble or cell bound) form of biotin. This MAb is highly specific to biotin and shows no cross-reaction with other structurally related compounds. It has a very high affinity for biotin and is excellent for use in various amplification techniques. In some applications, localization of biotinylated probes with avidin produces unacceptably high background staining. Anti-biotin antibody may be substituted to decrease this noise.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Anti-IgG Goat Polyclonal Antibody (CF™ 594)

Supplier: Biotium

Description: 2 mg/ml is prepared by labeling affinity purified igg with the biotin. the interaction of biotin with fluorescent labeled avidin or streptavidin gives significantly signal amplification.

Mix-n-Stain™ CF® Dye Antibody Labeling Kits, Biotium

Supplier: Biotium

Description: Label your antibody with one of our superior CF® Dyes in 30 minutes without a purification step. Labeling tolerates many common buffer components including BSA and ascites.

Alpha-Bungarotoxin, CF® Dye and Other Conjugates, Biotium

Supplier: Biotium

Description: Conjugates of alpha-bungarotoxin labeled with a selection of our CF® dyes and other labels. Labeled alpha-bungarotoxin conjugates can be used for staining nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections.

Human Recombinant Ubiquitin (from E. coli), Biotin

Catalog Number: (102890-702)

Supplier: R&D Systems

Description: The Recombinant Human Ubiquitin N-Terminal Biotin Protein from R&D Systems, powered by R&D Systems, powered by Boston Biochem is derived from E. coli. The Recombinant Human Ubiquitin N-Terminal Biotin Protein has been validated for the following applications: Enzyme Activity.

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Bovine AGE-BSA (from Serum), Biotin

Catalog Number: (220025-828)

Supplier: R&D Systems

Description: The Bovine AGE-BSA Biotinylated Protein from R&D Systems is derived from Bovine Serum. The Bovine AGE-BSA Biotinylated Protein has been validated for the following applications: Bioactivity.

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Anti-TACSTD1 Mouse Monoclonal Antibody (Biotin) [clone: EGP40/826 EGP40/837 EGP40/1110 EGP40/1120]

Supplier: Biotium

Description: This is a cocktail of four highly specific monoclonal antibodies (EGP40/826, EGP40/837, EGP40/1110, EGP40/1120) that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (Ep-CAM). It is a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or Ep-CAM. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.

Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Anti-IgG Mouse Monoclonal Antibody (CF™ 594)

Catalog Number: (89411-294)

Supplier: Biotium

Description: CF594 antibodies are affinity-purified antibodies labeled with deep red CF594 dye which is spectrally similar to Alexa Fluor 594 or Texas Red dye but with significantly brighter fluorescence and with excellent photostability.

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Anti-SUMO2 & SUMO3 Mouse Monoclonal Antibody (Biotin) [clone: SM23/496]

Supplier: Biotium

Description: This MAb reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of AlzheimerÃ¢Â€Â™s disease.

Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.