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Image Unavailable-76111-022

Anti-DUX3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76111-022)
Supplier: Bioss
Description: DUX3 belongs to the paired homeobox family and contains 2 homeobox DNA-binding domains. It expressed in hepatoma Hep3B cells. DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and of a poly(A) addition signal. Two different isoforms are known.
Image Unavailable-10424-640

Anti-CRNN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10424-640)
Supplier: Bioss
Description: This gene encodes a member of the "fused gene" family of proteins, which contain N terminus EF hand domains and multiple tandem peptide repeats. The encoded protein contains two EF hand Ca2+ binding domains in its N terminus and two glutamine and threonine rich 60 amino acid repeats in its C terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
Product Image-10204-980

Handheld Fluorimeter, ANDalyze

Catalog Number: (10204-980)
Supplier: ANDalyze Inc
Description: The AND1100 Fluorimeter tests for metals in water in two steps and less than two minutes, significantly reducing the test expenditures, complexity and wait times experienced in traditional tests. Powered by DNA, it is a breakthrough in streamlining the water analysis and reporting processes. The AND1100 Fluorimeter is a platform centric portable device for heavy metals testing for drinking water and industrial water supplies. It uses an extremely sensitive measurement technique in tandem with ANDalyze sensor kits to determine the toxicity levels of heavy metal contamination. Sensor kits are available for lead, uranium, copper, mercury, zinc, and cadmium; with more to come.
Product Image-77463-042

Cy5-SSL-NHS ester, ReadiCleave™

Catalog Number: (77463-042)
Supplier: AAT BIOQUEST INC
Description: ReadiCleave™ Cy5-SSL-NHS ester contains a S-S linker that can be cleaved with TCEP or DTT to remove the Cy5 fluorophore from the target molecule.
Image Unavailable-76108-968

Anti-CTDSPL Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76108-968)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Image Unavailable-76111-024

Anti-DUX3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76111-024)
Supplier: Bioss
Description: DUX3 belongs to the paired homeobox family and contains 2 homeobox DNA-binding domains. It expressed in hepatoma Hep3B cells. DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and of a poly(A) addition signal. Two different isoforms are known.
Product Image-76484-952

Cy5 biotin conjugate biodetection

Catalog Number: (76484-952)
Supplier: AAT BIOQUEST INC
Description: This bifunctional Cy5 biotin conjugate demonstrates excellent avidin binding and strong fluorescence.

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Product Image-77461-760

Cal-590L®/Cy5-Dextran conjugate, M.W. 10000, RatioWorks™

Catalog Number: (77461-760)
Supplier: AAT BIOQUEST INC
Description: RatioWorks™ Cal-590L/Cy5-Dextran Conjugate carries a calcium-independent Cy5 fluorphore as a reference color for radiometric measurements.
Product Image-10107-482

Anti-KLHL3 Rabbit Polyclonal Antibody

Catalog Number: (10107-482)
Supplier: Prosci
Description: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Image Unavailable-75963-352

Anti-MUC1 Mouse Monoclonal Antibody (CF640R) [clone: 139H2]

Supplier: Biotium
Description: This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-75963-356

Anti-MUC1 Mouse Monoclonal Antibody (CF647) [clone: 139H2]

Supplier: Biotium
Description: This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Image Unavailable-10410-292

Anti-PTPRA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10410-292)
Supplier: Bioss
Description: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
Image Unavailable-10480-054

Anti-CTDSPL Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10480-054)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Image Unavailable-10410-196

Anti-PTPRA Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10410-196)
Supplier: Bioss
Description: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
Image Unavailable-10410-288

Anti-PTPRA Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10410-288)
Supplier: Bioss
Description: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
Image Unavailable-10410-198

Anti-PTPRA Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10410-198)
Supplier: Bioss
Description: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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