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Catalog Number: (75817-116)
Supplier: Cayman Chemical Company
Description: A sensitive tool for measuring β-HB levels in plasma, serum, or urine.


Supplier: Adipogen
Description: Flow cytometry measurement tool. Fluorescence probe for glutathione and glutathione disulfide levels, primary amines, peptides and biological thiols. Reacts with primary amines to produce a product that emits a highly fluorescent blue colour. Spectral data: lambdaex 334 nm; lambdaem 455 nm (Thiol Adduct). Used for the quick visualization of histamine, characterized by the appearance of a yellow stain. Used for precolumn derivatization of amino acids for HPLC separation. High-level disinfectant/sterilant for endoscopes, thermometers, rubber and plastic equipment, and medical/surgical instruments that cannot be sterilized by heat, based on its antimicrobial efficacy and low inhalation toxicity.

Catalog Number: (52428-764)
Supplier: Caframo
Description: Wide base and H configuration provide excellent stability for bench top stirrers, including high torque line - Models BDC1850 (58960-447), BDC3030 (77776-348), BDC6015 (77776-354), BDC2010 (97001-136) and BDC2002 (77776-540).


Catalog Number: (102060-146)
Supplier: Affymetrix, Inc.
Description: Each Module Set is sufficient for ten 96-well microtiter plates and are identical to eBioscience high quality ready-to-use Conventional ELISAs. Cytochrome c was identified as a component required for the crucial steps in apoptosis, caspase-3 activation and DNA fragmentation. Cytochrome c was shown to redistribute from mitochondria to cytosol during apoptosis in intact cells.
Mitochrondrial cytochrome c is a water?soluble protein of 15 kDa with a net positive charge, residing loosely attached in the mitochrondrial intermembrane space. Cytochrome c functions in the respiratory chain by interaction with redox partners. The release of cytochrome c into the cytosol leads to an activation of an apoptotic program via activation of a caspase dependent pathway. Cytochrome c achieves this goal by interaction with other cytosolic factors forming a complex (apoptosome) composed of cytochrome c, Apaf-1, dATP and Apaf-3/caspase 9. Bcl-2 on the other hand was shown to be able to prevent apoptosis by blocking the release of cytochrome c from mitochondria. Measurement of cytochrome c release from the mitochondria is a tool to detect the first early steps for initiating apoptosis in cells. Moreover, elevated cytochrome c levels were observed in serum from patients with hematological malignancies. In the course of cancer chemotherapy, the serum-cytochrome c level grew rapidly and it decreased gradually as the patient was cleared from malignant cells. Thus, serum-cytochrome c monitoring might serve as a clinical marker indicating the onset of apoptosis and cell turn-over in vivo.

Blocked

Catalog Number: (102059-970)
Supplier: Affymetrix, Inc.
Description: Each Module Set is sufficient for ten 96-well microtiter plates and are identical to eBioscience high quality ready-to-use Conventional ELISAs. Superoxide Dismutases (SODs) are a unique family of metalloproteins that catalyze the dismutation of superoxide anion radicals (O2-) to oxygen (O2) and hydrogen peroxide (H2O2)O2- + O2- + 2H+ => H2O2 + O2SOD is ubiquitous in oxygen metabolizing cells protecting these cells against direct and indirect oxygen-mediated free radical damage. Four types of SOD have been defined on the basis of distinctions in their metal cofactors and distribution: Manganese (MnSOD) principally located in the matrix of mitochondria of all aerobes, copper/zinc (Cu/ZnSOD) mainly present in the cytoplasm of eukaryotic cells, iron (FeSOD), predominantly in the cytosol, chloropasts or mitochondria of prokaryotes as well as extracellular (ECSOD), which is found in the extracellular fluids or membrane associated in mammals. The properties of Cu/Zn superoxide dismutase are quite different from those of the manganese or iron enzymes. Induction of Cu/ZnSOD expression resulting in elevated levels of Cu/ZnSOD in human body fluids is of diagnostic value for measuring the activity of different diseases: NephropathiesCu/ZnSOD determination provides a tool for early diagnosis of nephropathies. Monitoring of therapeutic treatmentsCu/ZnSOD is a useful therapeutic tool in the treatment of chronic inflammation e.g. rheumatoid arthritis or of the ischemic myocardium in the phase of reperfusion. Due to the short half-life of SOD injected into the blood circulation, a rapid assay is necessary for monitoring SOD levels. Trisomy 21 (Down's Syndrome)In cases with Down's Syndrome an additional part of chromosome 21 is present in the genome of the patient as a structural chromosome aberration. The Cu/ZnSOD gene is localized on chromosome 21, closely associated with the gene complex responsible for the phenotype of Down's Syndrome. A gene-dosage effect for Cu/ZnSOD in Down's Syndrome providing a diagnostic marker for this syndrome has been described.a) Patients with Down's Syndrome have significantly elevated serum and urine levels of Cu/ZnSOD.b) Prenatal diagnosis of Down's Syndrome: Cu/ZnSOD levels are
quantitated from erythrocytes of fetal umbilical vein blood and related to the number of cells, the content of haemoglobin and to the haematocrit. In case of Trisomy 21 the significantly elevated levels of Cu/ZnSOD are determined.

Blocked

Supplier: Affymetrix, Inc.
Description: The human Cu/ZnSOD ELISA is an enzyme-linked immunosorbent
assay for the quantitative detection of human Cu/ZnSOD. The human
Cu/ZnSOD ELISA is for research use only. Not for diagnostic or
therapeutic procedures. Superoxide Dismutases (SODs) are a unique family of
metalloproteins that catalyze the dismutation of superoxide anion
radicals (O2-) to oxygen (O2) and hydrogen peroxide (H2O2)O2- + O2- + 2H+ => H2O2 + O2SOD is ubiquitous in oxygen metabolizing cells protecting these cells against direct and indirect oxygen-mediated free radical damage. Four types of SOD have been defined on the basis of distinctions in their metal cofactors and distribution: Manganese (MnSOD) principally located in the matrix of mitochondria of all aerobes, copper/zinc (Cu/ZnSOD) mainly present in the cytoplasm of eukaryotic cells, iron (FeSOD), predominantly in the cytosol, chloropasts or mitochondria of prokaryotes as well as extracellular (ECSOD), which is found in the extracellular fluids or membrane associated in mammals. The properties of Cu/Zn superoxide dismutase are quite different from those of the manganese or iron enzymes. Induction of Cu/ZnSOD expression resulting in elevated levels of
Cu/ZnSOD in human body fluids is of diagnostic value for measuring the activity of different diseases: NephropathiesCu/ZnSOD determination provides a tool for early diagnosis of
nephropathies. Monitoring of therapeutic treatmentsCu/ZnSOD is a useful therapeutic tool in the treatment of chronic
inflammation e.g. rheumatoid arthritis or of the ischemic myocardium in the phase of reperfusion. Due to the short half-life of SOD injected into the blood circulation, a rapid assay is necessary for monitoring SOD levels. Trisomy 21 (Down's Syndrome)In cases with Down's Syndrome an additional part of chromosome 21 is present in the genome of the patient as a structural chromosome aberration. The Cu/ZnSOD gene is localized on chromosome 21, closely associated with the gene complex responsible for the phenotype of Down's Syndrome. A gene-dosage effect for Cu/ZnSOD in Down's Syndrome providing a diagnostic marker for this syndrome has been described.a) Patients with Down's Syndrome have significantly elevated serum and urine levels of Cu/ZnSOD.b) Prenatal diagnosis of Down's Syndrome: Cu/ZnSOD levels are quantitated from erythrocytes of fetal umbilical vein blood and related to the number of cells, the content of haemoglobin and to the haematocrit. In case of Trisomy 21 the significantly elevated levels of Cu/ZnSOD are determined.

Catalog Number: (MFLX43299-12)
Supplier: VWR International
Description: Measure level without touching fluid to avoid contamination.

IP68 washdown


Supplier: VWR International
Description: The VWR® Crosslinker’s overhead 254nm UV is used not only for attaching nucleic acids to a membrane, but also for sterilization and decontamination of plates, small tools, etc.

Small Business Enterprise Product available on GSA Advantage®

Catalog Number: (470219-588)
Supplier: VWR International
Description: The Current Balance is an excellent tool for studying electric currents.


Supplier: VWR International
Description: Used with the VWR* CryoPro* AF, BR, and CC Series cryostorage containers.

Small Business Enterprise Product available on GSA Advantage®

Catalog Number: (10803-214)
Supplier: Restek
Description: Recommended for inlet liners with an ID ≥2 mm.


Catalog Number: (89132-992)
Supplier: QLA
Description: Digital Depth Gage Assembly for accurate measurement of Dissolution Paddle and Basket height within the dissolution vessel.


Catalog Number: (470174-956)
Supplier: KONUS USA CORP.
Description: This multi-functional tool provides accurate measurements in all three parameters.


Catalog Number: (75816-762)
Supplier: Cayman Chemical Company
Description: Simple, reproducible, and sensitive tool for measurement of glycerol in plasma and serum.


Catalog Number: (10852-900)
Supplier: Restek
Description: Set comes with screwdrivers, pliers, wrenches, sockets, scissors, clamps, and more.


Supplier: IKA Works
Description: Made of stainless steel

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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