You Searched For: IDO-IN-2


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Catalog Number: (75791-954)
Supplier: Prosci
Description: Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.


Catalog Number: (103274-168)
Supplier: Novus Biologicals
Description: The Indoleamine 2,3-dioxygenase / IDO Antibody from Novus Biologicals is a rabbit polyclonal antibody to Indoleamine 2,3-dioxygenase / IDO. This antibody reacts with human. The Indoleamine 2,3-dioxygenase / IDO Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin.


Catalog Number: (102514-462)
Supplier: Adipogen
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.


Catalog Number: (102514-788)
Supplier: Adipogen
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

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Catalog Number: (75793-316)
Supplier: Prosci
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.


Catalog Number: (77206-278)
Supplier: ANTIBODIES.COM LLC
Description: Human IDO-2 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i><i>in vitro</i></i> quantitative determination of human IDO-2 in serum, plasma, and other biological fluids.


Catalog Number: (RL600-401-J44)
Supplier: Rockland Immunochemical
Description: Anti-IDO antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~41kDa corresponding to the appropriate cell lysate or extract.


Catalog Number: (RL600-401-J43)
Supplier: Rockland Immunochemical
Description: Anti-IDO antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~41kDa corresponding to the appropriate cell lysate or extract.


Supplier: Ambeed
Description: NLG919 98%

New Product

Catalog Number: (MSPP-RPB547HU1)
Supplier: CLOUD-CLONE CORP MS
Description: This is a IDO recombinant protein (prokaryotic), Human is sequencing from Ala2~Gly403 with 97 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

New Product


Catalog Number: (76699-024)
Supplier: AFG BIOSCIENCE LLC
Description: Human Indoleamine 2,3-Dioxygenase(IDO) ELISA Kit


Catalog Number: (75793-540)
Supplier: Prosci
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.


Catalog Number: (76201-754)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, Flow Cytometry, IHC, WB

Species reactivity: Human


Catalog Number: (103274-170)
Supplier: Novus Biologicals
Description: The Indoleamine 2,3-dioxygenase / IDO Antibody from Novus Biologicals is a rabbit polyclonal antibody to Indoleamine 2,3-dioxygenase / IDO. This antibody reacts with human. The Indoleamine 2,3-dioxygenase / IDO Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.


Catalog Number: (MSPP-SEB547HU)
Supplier: CLOUD-CLONE CORP MS
Description: This assay has high sensitivity and excellent specificity for detecting Human IDO (Indoleamine to 2,3-Dioxygenase). The assay range is from 0.312 to 20 ng/ml (Sandwich kit) with a sensitivity of 0.127 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

New Product


Catalog Number: (75793-322)
Supplier: Prosci
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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