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Catalog Number: (97039-646)
Supplier: Sper Scientific
Description: Government organizations such as OSHA have set recommended heat stress limits for various activities


Supplier: Sper Scientific
Description: Takes the guesswork out of heat stress calculations.

Catalog Number: (470222-121)
Supplier: NIELSEN-KELLERMAN CO
Description: The Kestrel 3500 has the most functions of any Kestrel Meter in the 3000 series. It measures wind speed, relative humidity, temperature, wet bulb temperature (psychrometric), altitude, pressure trend, barometric pressure, heat stress index, dew point temperature, wind chill.


Supplier: VWR International
Description: The VWR® series Moisture Analyzers offer precise and reliable results for moisture content analysis.

Catalog Number: (76481-930)
Supplier: AAT BIOQUEST INC
Description: Hydrogen peroxide (H2O2) is a reactive oxygen metabolic by-product that serves as a key regulator for a number of oxidative stress-related states.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (76483-832)
Supplier: AAT BIOQUEST INC
Description: Reactive oxygen species (ROS) are natural byproducts of the normal metabolism of oxygen and play important roles in cell signaling.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (76481-934)
Supplier: AAT BIOQUEST INC
Description: Hydrogen peroxide is a reactive oxygen metabolic by-product that serves as a key regulator for a number of oxidative stress-related states.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Supplier: Enzo Life Sciences
Description: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

Supplier: Enzo Life Sciences
Description: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

Catalog Number: (76481-932)
Supplier: AAT BIOQUEST INC
Description: Hydrogen peroxide is a reactive oxygen metabolic by-product that serves as a key regulator for a number of oxidative stress-related states.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (76481-936)
Supplier: AAT BIOQUEST INC
Description: Hydrogen peroxide is a reactive oxygen metabolic by-product that serves as a key regulator for a number of oxidative stress-related events.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (103422-208)
Supplier: Affymetrix, Inc.
Description: Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6. 0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is colon carcinoma. A wide variety of environmental and pathophysiological stressful condition triggers the synthesis of heat shock proteins or stress response proteins. HSP60 is a potential antigen in a number of autoimmune diseases including human arthritis.

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Catalog Number: (76120-446)
Supplier: Bioss
Description: JWA is a four-transmembrane environmental responsive protein which binds to the CC chemokine receptor 5 (CCR5), a major co-receptor for human immunodeficiency virus (HIV). JWA is involved in environmental stress-responsive pathways in K562 cells, an erythroleukemia cell line derived from patients with chronic myeloid leukemia. Environmental stressors to K562 cells such as heat shock, a higher temperature than the ideal body temperature of the organism from which the cell line was derived, and oxidative stress, the production of oxygen-centered free radicals, regulate and increase the expression of JWA. This response to environmental stressors suggests similarity of JWA to heat shock protein 70 (HSP70), which is upregulated by heat stress and toxic chemicals.


Catalog Number: (76483-824)
Supplier: AAT BIOQUEST INC
Description: Reactive oxygen species (ROS) are natural byproducts of the normal metabolism of oxygen and play important roles in cell signaling.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Supplier: Enzo Life Sciences
Description: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

Catalog Number: (103471-080)
Supplier: Affymetrix, Inc.
Description: MA3-009 detects heat shock protein 70 kDa (HSP70) from mouse and human tissues. This antibody specifically detects HSP70 and does not cross-react with other members of the HSP70 family. MA3-009 has been successfully used in Western blot, IF, blocking, FACS, inhibition assay, immunohistochemistry, and immunoprecipitation procedures. By Western blot, this antibody detects a 70 kDa protein representing HSP70 from K562 cell extract. The MA3-009 antigen is recombinant human HSP70 over-expressed in E. coli. Epitope mapping with a panel of HSP70 deletion mutants suggests that the epitope recognized is located between amino acids 504-617 of human HSP70, a region that has been shown to be involved in stress-induced nucleolar localization. Heat shock proteins (HSP) are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs including HSP70, HSP90 and HSP100. The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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