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You Searched For: Erlotinib


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Erlotinib 95%

Supplier: Ambeed
Description: Erlotinib 95%

New Product

Product Image-77694-332

Erlotinib-d6 Hydrochloride, TRC, LGC Standards

Catalog Number: (77694-332)
Supplier: LGC STANDARDS
Description: Erlotinib-d6 Hydrochloride, TRC, LGC Standards

New Product


Image Unavailable-77454-310

Pharmaceutical Standards, Erlotinib Impurity 47

Supplier: TLC Standards
Description: Pharmaceutical Standards, Erlotinib Impurity 47

New Product

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N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95%

Supplier: Adipogen
Description: Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that Erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is <gt/>1000-fold more sensitive for EGFR than for c-Src or v-Abl.

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N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95% (by HPLC)

Catalog Number: (76003-114)
Supplier: Enzo Life Sciences
Description: EGFR tyrosine kinase auto-phosphorylation inhibitor
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Pharmaceutical Standards, Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl

Supplier: TLC Standards
Description: Pharmaceutical Standards, Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl

New Product

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Pharmaceutical Standards, Erlotinib HCl

Supplier: TLC Standards
Description: Pharmaceutical Standards, Erlotinib HCl

New Product

Product Image-77697-415

Erlotinib Hydrochloride, Mikromol, LGC Standards

Catalog Number: (77697-415)
Supplier: LGC STANDARDS
Description: Erlotinib Hydrochloride, Mikromol, LGC Standards

New Product


Product Image-TS46233-0050

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

Catalog Number: (TS46233-0050)
Supplier: Thermo Scientific Chemicals
Description: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
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N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95%

Supplier: Matrix Scientific
Description: MF=C22H24CLN3O4 MW=429.91 CAS=183319-69-9 MDL=MFCD07781272 1G

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Pharmaceutical Standards, Erlotinib Impurity 36 HCl

Supplier: TLC Standards
Description: Pharmaceutical Standards, Erlotinib Impurity 36 HCl

New Product

Image Unavailable-77615-260

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride 98%

Supplier: Ambeed
Description: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride 98%

New Product

Image Unavailable-10265-150

Anti-RAPGEF5 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10265-150)
Supplier: Bioss
Description: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.
Image Unavailable-10259-556

Anti-RAPGEF5 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10259-556)
Supplier: Bioss
Description: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.
Image Unavailable-10259-558

Anti-RAPGEF5 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10259-558)
Supplier: Bioss
Description: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.
Image Unavailable-10259-560

Anti-RAPGEF5 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10259-560)
Supplier: Bioss
Description: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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