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Anti-Protein A Mouse Monoclonal Antibody [clone: 4F9A8]

Catalog Number: (77007-544)
Supplier: Genscript
Description: Protein A, a bacterial cell wall protein isolated from Staphylococcus aureus, binds to mammalian IgGs mainly through Fc regions. The Protein A is most commonly bound to a chromatography resin, used for production of antibody drugs or reagents. Protein A antibody can be used for quantification of Protein A in drugs and foods or for evaluation of Protein A resin. This Protein A mAb is advantageous due to its IgG1 isotype, for mouse IgG1 has weak binding capacity to Protein A. GenScript Protein A Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with purified recombinant Protein A.
Product Image-12777-042

BioCoat™ HTS Caco-2 Assay Systems, PET Membrane, Corning

Catalog Number: (12777-042)
Supplier: Corning
Description: HTS insert plates are arrays of individual cell culture inserts connected by a rigid, robotics-friendly holder. This single-unit design makes insert plates ideal for running automated, high throughput drug transport (Caco-2 cells) cell toxicity studies or cell migration and invasion studies.

Environmentally Preferable


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Shea butter

Supplier: Spectrum Chemicals
Description: Shea Butter, a fat extracted from the African Shea tree nut, is a triglyceride derived from oleic acid and stearic acid. The U.S. Food and Drug Administration (FDA), also considers shea butter to be edible: Generally Recognized as Safe (GRAS3) and shea can be used in confectionery coatings or fillings, in the US. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes.

Small Business Enterprise

Image Unavailable-10434-354

Anti-CYP2W1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10434-354)
Supplier: Bioss
Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Product Image-76347-270

β-Nicotinamide adenine dinucleotide

Supplier: RPI
Description: β-Nicotinamide-Adenine Dinucleotide, Oxidized Form (β-NAD) is suitable for Enzyme synthesis / Biocatalysis applications. It is also applicable for making Enzyme Multiplied Immunoassay Technique (EMIT), Therapeutic Drug monitoring (TDM) and Blood Glucose reagents.

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ProPac™ 3R SCX 3 μm HPLC Columns

Supplier: Thermo Scientific
Description: Use Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC columns to provide the reproducibility, resolution, and robustness needed for protein characterization. These columns are ideal for charge variant analysis and recommended for use with therapeutic proteins, monoclonal antibodies (mAbs), antibody drug conjugates (ADCs), and biosimilar proteins.

Product Image-10108-628

Anti-GSTM1 Rabbit Polyclonal Antibody

Catalog Number: (10108-628)
Supplier: Prosci
Description: Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Product Image-76635-850

HyClone™ CHO Cell Culture Platform Media, SFM4CHO Utility Powder (HyClone products (Cytiva))

Catalog Number: (76635-850)
Supplier: Cytiva
Description: HyClone™ SFM4CHO-Utility media is ideally suited for the cost-effective manufacturing of recombinant proteins for academic and industrial research, genomics and proteomics, drug target screening and validation, and manufacturing of preclinical lots. It is formulated using a proprietary lipid complexing process for enhanced stability and broad-spectrum growth promotion.
Image Unavailable-77007-476

Anti-Bevacizumab Mouse Monoclonal Antibody [clone: 11C1]

Catalog Number: (77007-476)
Supplier: Genscript
Description: Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumours growth and metastasis by weakening tumour angiogenesis.
Image Unavailable-CH03283-100MG

Ala-Gly-Gly-Gly-OH

Catalog Number: (CH03283-100MG)
Supplier: CHEM-IMPEX INTERNATIONAL, INC
Description:
Ala-Gly-Gly-Gly-OH, also known as A Glycine derivative, is a peptide that plays a significant role in various biochemical applications. This compound is particularly valued in the fields of biochemistry and molecular biology for its ability to serve as a building block in peptide synthesis. Its unique structure allows it to participate in the formation of larger peptides and proteins, making it essential for researchers focused on protein engineering and drug development. Additionally, Ala-Gly-Gly-Gly-OH has been explored for its potential therapeutic applications, including its role in enhancing the stability and efficacy of peptide-based drugs.

Researchers and industry professionals can leverage Ala-Gly-Gly-Gly-OH in the development of novel therapeutic agents, particularly in the areas of cancer treatment and regenerative medicine. Its compatibility with various biochemical assays and its ability to modulate biological activity make it a versatile tool in laboratory settings. Furthermore, its relatively simple synthesis and stability under physiological conditions provide significant advantages over more complex peptides, making it an attractive option for both academic and industrial applications.

New Product


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Poly(D-lactide), M.W. 90000-124000 g/mol, (max. 0.5% H₂O)

Supplier: Adipogen
Description: Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds.

Image Unavailable-89156-284

SCREEN-WELL® GABAergic Ligand Library, Enzo Life Sciences

Supplier: Enzo Life Sciences
Description: The GABAergic Ligands library contains 56 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs.

Image Unavailable-10320-894

Anti-COMT Rabbit Polyclonal Antibody (Cy5)

Catalog Number: (10320-894)
Supplier: Bioss
Description: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Product Image-10108-932

Anti-UGT1A1 Rabbit Polyclonal Antibody

Catalog Number: (10108-932)
Supplier: Prosci
Description: UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
Product Image-10101-204

Anti-KCNQ2 Rabbit Polyclonal Antibody

Catalog Number: (10101-204)
Supplier: Prosci
Description: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
Product Image-16171-669

Straight Plug Rubber Stoppers, Wheaton

Catalog Number: (16171-669)
Supplier: DWK Life Sciences (KIMBLE)
Description: Wheaton straight plug stoppers provide maximum sealing for vials with a straight-wall glass finish

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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