You Searched For: Cytosine

Catalog Number: (76009-558)

Supplier: Prosci

Description: mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.

Supplier: MP Biomedicals

Description: Deoxyribonucleic Acid is a polynucleotide . It is an essential component of chromosomes in cell nuclei. It is the carrier of genetic material. It contains information in chemical code to direct the development of the cell according to its inheritance. The purine and pyrimidine bases of the nucleosides are primarily adenine, guanine, cytosine and thymine. The sugar is D-2-deoxyribose. The nucleosides are linked together by phosphates in diester linkage from the 3'-hydroxyl of one sugar to the 5'-hydroxyl of the next. The repeating sugar-phosphate linkage forms the backbone of the single polynucleotide strand which is the primary structure of DNA. Chemical analysis of DNA from different species show that the purine content is equal to the pyrimidine content; adenine content equal to thymine; guanine equal to cytosine. DNA also acts as a template in the formation of ribonucleic acids, which play a fundamental role in the synthesis of proteins in the cell.

SDS

Catalog Number: (10433-572)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Catalog Number: (10433-576)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Supplier: TCI America

Description: CAS Number: 134678-17-4
MDL Number: MFCD00869739
Molecular Formula: C8H11N3O3S
Molecular Weight: 229.25
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 177
Specific rotation [a]20/D: -142 deg (C=1, MeOH)
Storage Temperature: <0°C

SDS Certificates

Supplier: Ambeed

Description: 5-Aza-2'-deoxycytidine 99%

New Product

Catalog Number: (10433-554)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Catalog Number: (10454-402)

Supplier: Bioss

Description: Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.

Supplier: TCI America

Description: CAS Number: 10212-25-6
MDL Number: MFCD00012636
Molecular Formula: C9H11N3O4
Molecular Weight: 261.66
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 264
Specific rotation [a]20/D: -21 deg (C=2, H2O)

SDS Certificates

Supplier: Ambeed

Description: 5-Fluorocytosine 97%

Catalog Number: (10801-166)

Supplier: Rockland Immunochemical

Description: DNMT1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities (1). DNMT1 enzyme is crucial for stable expression and function in vivo (2). DNMT1 is essential for maintenance of DNA methylation and the interaction of DNMT1 with the replication machinery is not strictly necessary for maintenance of DNA methylation, but improves its efficiency. DNMT1 is necessary and sufficient to maintain global methylation and aberrant CpG island methylation in human cancer cells. DNMT1 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.

Catalog Number: (76117-932)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Catalog Number: (10433-568)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Catalog Number: (10433-570)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.

Catalog Number: (77437-268)

Supplier: Bioss

Description: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

Catalog Number: (10433-566)

Supplier: Bioss

Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.