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Catalog Number: (10433-574)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Supplier: Ambeed
Description: 5-Aza-2'-deoxycytidine 99%

New Product

Supplier: TCI America
Description: CAS Number: 2353-33-5
MDL Number: MFCD00043011
Molecular Formula: C8H12N4O4
Molecular Weight: 228.21
Form: Crystal
Color: White
Melting point (°C): 191
Specific rotation [a]20/D: 68.5 deg (C=0.5, H2O)
Storage Temperature: 0-10°C
Catalog Number: (10433-554)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Catalog Number: (103255-546)
Supplier: RevMAb Biosciences
Description: This antibody reacts to 5-hydroxymethylcytosine in both single-stranded and double-stranded DNA. No cross reactivity with non-methylated cytosine and methylcytosine in DNA.


Supplier: MORAVEK BIOCHEMICALS MS
Description: 5-Aza-2'-deoxycytidine

Catalog Number: (76117-932)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Supplier: MP Biomedicals
Description: Deoxyribonucleic Acid is a polynucleotide . It is an essential component of chromosomes in cell nuclei. It is the carrier of genetic material. It contains information in chemical code to direct the development of the cell according to its inheritance. The purine and pyrimidine bases of the nucleosides are primarily adenine, guanine, cytosine and thymine. The sugar is D-2-deoxyribose. The nucleosides are linked together by phosphates in diester linkage from the 3'-hydroxyl of one sugar to the 5'-hydroxyl of the next. The repeating sugar-phosphate linkage forms the backbone of the single polynucleotide strand which is the primary structure of DNA. Chemical analysis of DNA from different species show that the purine content is equal to the pyrimidine content; adenine content equal to thymine; guanine equal to cytosine. DNA also acts as a template in the formation of ribonucleic acids, which play a fundamental role in the synthesis of proteins in the cell.

SDS

Catalog Number: (10433-570)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Catalog Number: (10433-566)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Catalog Number: (10433-568)
Supplier: Bioss
Description: TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.


Supplier: TCI America
Description: CAS Number: 134678-17-4
MDL Number: MFCD00869739
Molecular Formula: C8H11N3O3S
Molecular Weight: 229.25
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 177
Specific rotation [a]20/D: -142 deg (C=1, MeOH)
Storage Temperature: <0°C
Catalog Number: (101095-014)
Supplier: USP
Description: (200 mg)

SDS


Catalog Number: (10801-166)
Supplier: Rockland Immunochemical
Description: DNMT1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities (1). DNMT1 enzyme is crucial for stable expression and function in vivo (2). DNMT1 is essential for maintenance of DNA methylation and the interaction of DNMT1 with the replication machinery is not strictly necessary for maintenance of DNA methylation, but improves its efficiency. DNMT1 is necessary and sufficient to maintain global methylation and aberrant CpG island methylation in human cancer cells. DNMT1 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.


Catalog Number: (76009-408)
Supplier: Prosci
Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined.


Catalog Number: (10454-402)
Supplier: Bioss
Description: Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.


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