You Searched For: CP-55,940

Catalog Number: (10510-864)

Supplier: General Separation Technologies, Inc.

Description: Typical Application: 5% Fragrance Materials Association Mix, Acrylate Impurities II, Antidepressants (Basic Drugs- Uncategories), Antiepileptics, Barbiturates (Acidic/Neutral Drugs-Underivatized), Fentanyls, Organochlorine Pesticides III, Phenoxy Acid Herbicides, Styrene Impurities, TMS derivatized Sugars, Triazine Herbicides I, VOCs in Packaging materials.

Catalog Number: (10165-082)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to MRP8

Catalog Number: (76082-672)

Supplier: Bioss

Description: S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF-kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK. .

Supplier: Adipogen

Description: Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin, but it does not inhibit NLRP1, NLRC4, AIM2, TLR2 signaling or priming of NLRP3. Prevents oligomerization of ASC in cells stimulated with LPS and nigericin. Active in vivo, blocking the production of IL-1beta and enhancing survival in mouse models of multiple sclerosis and cryopyrin-associated periodic syndrome (CAPS). Also active in ex vivo samples from individuals with Muckle-Wells syndrome. Potential therapeutic agent for NLRP3-associated syndromes, including autoinflammatory and autoimmune diseases.

Catalog Number: (10510-876)

Supplier: General Separation Technologies, Inc.

Description: Typical Application: 5% Fragrance Materials Association Mix, Acrylate Impurities II, Antidepressants (Basic Drugs- Uncategories), Antiepileptics, Barbiturates (Acidic/Neutral Drugs-Underivatized), Fentanyls, Organochlorine Pesticides III, Phenoxy Acid Herbicides, Styrene Impurities, TMS derivatized Sugars, Triazine Herbicides I, VOCs in Packaging materials.

Catalog Number: (75850-022)

Supplier: Restek

Description: These general-purpose columns are designed for solvent impurities, PCB congeners, simulated distillation, drugs of abuse, gases, natural gas odorants, sulfur compounds, essential oils, hydrocarbons, semi-volatiles, pesticides, and oxygenates.

Catalog Number: (10795-414)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to MRP8

Catalog Number: (10759-486)

Supplier: Biolegend

Description: Purified anti-human CD184 (CXCR4) (MaxPar® Ready) [12G5]; Isotype: Mouse IgG2a, κ; Reactivity: Human, African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Sooty Mangabey; Apps: FC, CyTOF®; Size: 100 μg

Supplier: Biolegend

Description: Brilliant Violet 605™ anti-human CD184 (CXCR4) [12G5]; Isotype: Mouse IgG2a, κ; Reactivity: Human, African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Sooty Mangabey; Apps: FC; Size: 100 tests

Catalog Number: (75851-742)

Supplier: Restek

Description: For the analysis of pesticides, PCBs, solvents, and drugs.

Catalog Number: (10850-344)

Supplier: Restek

Description: These gas chromatography columns are designed for the analysis of volatile organic compounds using a GC/MS system.

Supplier: Bulwark Protection

Description: This environment of ingenuity and innovation demands reliable lab PPE that provides the ultimate in protection and comfort, for all-day wear. That’s why Bulwark CP offers breakthrough safety wear designed specifically for the lab.

Supplier: Restek

Description: General-purpose columns for the analysis of FAMEs, flavor compounds, essential oils, amines, solvents, and xylene isomers.

Catalog Number: (10108-256)

Supplier: Prosci

Description: PCBP4 is a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G (2)-M.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G (2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G (2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

Supplier: Thermo Scientific Chemicals

Description: Uses: Thickener, binder, and emulsifier
Average MW 100,000; viscosity (5 wt% aqueous solution, 25°) 75-150 cps; As ³3ppm, Pb ³10ppm
Soluble in polar organic solvents, in water at room temperature

SDS Certificates

Catalog Number: (10104-850)

Supplier: Prosci

Description: The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.