You Searched For: CMH+hydrochloride

Supplier: Enzo Life Sciences

Description: Spin trapping reagent.

Supplier: Bel-Art Products, a Part of SP

Description: These white polystyrene plastic trays measure 36 x 44.5 x 5.7 cmH (14 x 17½ x 2¼”) and fit standard lab bench drawers.

Catalog Number: (103460-394)

Supplier: Affymetrix, Inc.

Description: Suggested positive control: Hela whole cell lysate, antigen standard for CASP7 (transient overexpression lysate), HeLa and Jurkat whole cell extracts, Jurkat whole cell lysate. Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions.

Catalog Number: (76084-676)

Supplier: Bioss

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

Catalog Number: (10802-286)

Supplier: Rockland Immunochemical

Description: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.

Catalog Number: (103471-030)

Supplier: Affymetrix, Inc.

Description: MA1-91896 detects Caspase 7 from mouse, rat, human samples. MA1-91896 has been successfully used in Western blot applications. The MA1-91896 immunogen is: Full-length recombinant human Caspase 7 protein Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; ini

Catalog Number: (89217-376)

Supplier: Bel-Art Products, a Part of SP

Description: Sturdy, stable polypropylene rack is made specifically for organizing and protecting thin-walled Nuclear Magnetic Resonance tubes.

Catalog Number: (103429-422)

Supplier: Affymetrix, Inc.

Description: PA5-32146 targets Caspase 7 p11 subunit in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-32146 immunogen is recombinant fragment corresponding to a region within amino acids 158 and 303 of Human Caspase 7 p11 subunit. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Catalog Number: (10802-284)

Supplier: Rockland Immunochemical

Description: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.

Catalog Number: (76084-678)

Supplier: Bioss

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

Catalog Number: (103468-136)

Supplier: Affymetrix, Inc.

Description: Suggested positive control: Jurkat, antigen standard for CASP7 (transient overexpression lysate), Jurkat whole cell lysate. Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Caspase-7 is derived from the cleavage of proMCH3-alpha into 2 subunits, p20 and p12 by Caspase-3. Sequence analysis revealed that the MCH3-alpha amino acid sequence had the highest homology to caspase-3 (53% identity) and less than 37% identity with all other family members.

Catalog Number: (103470-782)

Supplier: Affymetrix, Inc.

Description: MA1-91217 detects Caspase 7 from mouse, rat, human samples. MA1-91217 has been successfully used in immunoprecipitation, Western blot applications. The MA1-91217 immunogen is: Available on request. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; ini

Catalog Number: (103460-100)

Supplier: Affymetrix, Inc.

Description: A suggested positive control for this product is MCF-7 cell lysate. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Catalog Number: (103460-074)

Supplier: Affymetrix, Inc.

Description: Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Catalog Number: (10118-204)

Supplier: VWR

Description: L-Ornithine hydrochloride grade: reagent CAS Number: 3184-13-2 synonym(s): (S)?-?(+)?-?2, 5-?Diaminopentanoic Acid Hydrochloride, (S)?-?2, 5-?Diaminopentanoic Acid Monohydrochloride, L-Ornithine Monohydrochloride 500g

SDS Certificates

Supplier: AVANTOR PERFORMANCE MATERIALS US

Description: Guanidine Hydrochloride, GenAR®

SDS Certificates