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Image Unavailable-10306-308

Anti-TERT Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10306-308)
Supplier: Bioss
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Image Unavailable-10306-306

Anti-TERT Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10306-306)
Supplier: Bioss
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Image Unavailable-76101-454

Anti-Menin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-454)
Supplier: Bioss
Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Image Unavailable-77871-510

Tris(pentafluorophenyl)borane ≥97%

Supplier: Ambeed
Description: Tris(pentafluorophenyl)borane ≥97%

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Image Unavailable-75871-764

(±)-1-Methyl-3-phenylpropylamine

Catalog Number: (75871-764)
Supplier: Spectrum Chemicals
Description: 3-Amino-1-phenylbutane, purity: 98.0 %, CAS number: 22374-89-6, Molecular Formula: C10H15N, Molecular weight: 149.24, Color: Colorless, Form: Liquid, synonyms: 1-Methyl-3-phenylpropylamine ; 4-Phenyl-2-butylamine, size: 100 ml

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Product Image-TS35313-0050

Tris(pentafluorophenyl)borane 95%

Supplier: Thermo Scientific Chemicals
Description: Tris(pentafluorophenyl)borane 95%

Image Unavailable-10233-704

Anti-TERT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10233-704)
Supplier: Bioss
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Product Image-101809-312

1-Methyl-4-phenylbutylamine

Catalog Number: (101809-312)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 020049-500MG , MDL Number: MFCD07788354
Image Unavailable-10334-938

Anti-MEN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10334-938)
Supplier: Bioss
Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Image Unavailable-10233-700

Anti-TERT Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10233-700)
Supplier: Bioss
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Image Unavailable-10480-464

Anti-DHPS Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10480-464)
Supplier: Bioss
Description: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Image Unavailable-10306-314

Anti-TERT Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Catalog Number: (10306-314)
Supplier: Bioss
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Product Image-101810-890

2-Methoxybutylamine

Catalog Number: (101810-890)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 020853-500MG , MDL Number: MFCD06247961
Product Image-TS45775-0050

Diethyl(3-pyridyl)borane 97%

Supplier: Thermo Scientific Chemicals
Description: Diethyl(3-pyridyl)borane 97%

Image Unavailable-TCB2043-25ML

N-Butylbenzylamine ≥97.0% (by GC, titration analysis)

Catalog Number: (TCB2043-25ML)
Supplier: TCI America
Description: CAS Number: 2403-22-7
MDL Number: MFCD00009427
Molecular Formula: C11H17N
Molecular Weight: 163.26
Purity/Analysis Method: >97.0% (GC,T)
Form: Clear Liquid
Boiling point (°C): 182
Flash Point (°C): 94
Specific Gravity (20/20): 0.91

SDS Certificates


Image Unavailable-EM8.08358.2500

Tributylamine ≥99.0% (by GC) for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma
Description: Cas Number 102-82-9 1L

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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