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Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

Supplier: Cytiva
Description: Whatman GD/X Syringe Filters are high-viscosity filters that incorporate a prefilter to enable filtration of viscous, dense or otherwise hard-to-filter material with high solids content as in environmental and food analysis samples.
Catalog Number: (76741-142)
Supplier: ANTIBODIES.COM LLC
Description: Human PCBP1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human PCBP1 in serum, plasma, tissue homogenates, and other biological fluids.


Supplier: Cytiva
Description: The Whatman Mini-UniPrep Syringeless Filters combine four products into one syringeless filter solution for efficient chromatography sample preparation for a broad range of applications. They are built for fast and easy high performance liquid chromatography/ultra high performance liquid chromatography sample preparation and analysis.
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.

Supplier: Corning
Description: Syringe filters are available with a choice of membrane type: Polyethersulfone (PES) for low protein binding and faster flow rates; surfactant-free cellulose acetate (SFCA), with or without prefilter, for lowest protein binding; Polytetrafluoroethylene (PTFE) for chemical resistance; regenerated cellulose (RC) – the best choice for DMSO compatibility; and nylon (NY) which is hydrophilic, surfactant-free and lowest extractable.
Catalog Number: (89358-098)
Supplier: Genetex
Description: The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]


Catalog Number: (101381-656)
Supplier: Electron Microscopy Sciences
Description: PQ UNIVERSAL is a liquid concentrate dimezones/hydroquinone developer which is suitable for all RC and FB black and white photographic papers. It is used at a dilution of 1+9, it is clean working and it has excellent keeping properties. It gives a slightly warm neutral image tone with most papers. In addition, PQ UNIVERSAL can be used to dish/tray process ILFORD as well as some other technical films. It is also suitable for dish/tray developing of general purpose sheet films when a fast working, high contrast developer is needed and a high degree of enlargement is not required. PQ UNIVERSAL developer is designed for use at ambient room temperatures, normally 20°C/68°F. We do not recommend its use for high temperature or machine processing applications.

Minority or Woman-Owned Business Enterprise


Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Catalog Number: (10107-956)
Supplier: Prosci
Description: PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.


Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

Supplier: Cytiva
Description: SPARTAN syringe filters with regenerated cellulose (RC) membrane provide reproducible filtration of organic and aqueous solutions for high performance and ultra-high performance liquid chromatography (HPLC and UHPLC) sample preparation.
Supplier: Excelta
Description: These high-quality cutters are designed for cutting small soft wire up to 250,000 times without resharpening.

Small Business Enterprise Minority or Woman-Owned Business Enterprise

Catalog Number: (EM1.03164.0025)
Supplier: MilliporeSigma
Description: Eriochrome cyanine R for analysis, reagent for aluminium (C.I. 43820), Supelco®

Supplier: Spectrum Laboratories
Description: Nylon closures lock gently over rigid membranes such as cellulose ester (CE) and polyvinylidene fluoride (type F) tubing, providing a strong, leakproof seal

Small Business Enterprise

Supplier: VWR International
Description: Meets ACS specifications for general use.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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