You Searched For: AMP+PNP


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Catalog Number: (76292-930)
Supplier: Cayman Chemical Company
Description: Cyclic di-nucleotide phosphodiesterase (CdnP, also known as Rv2837c) is a soluble, stand-alone phosphodiesterase in regulating cyclic dinucleotide signaling during intracellular infections of <em>M. tuberculosis</em>{36095}. Studies have found that CdnP is capable of hydrolyzing cyclic di-adenosine monophosphate (c-di-AMP; Item No. 17753) into two AMPs as a strategy to avoid activation of the innate immune response of the host. <em>M. tuberculosis</em> infection leads to cytosolic release of c-di-AMP, which is recognized by stimulator of interferon genes (STING) and subsequently triggers type I interferon response. Other studies have shown that deletion or inhibition of CdnP attenuates the <em>M. tuberculosis</em> virulence both <em>in vitro</em> and <em>in vivo</em>.

Catalog Number: (103002-738)
Supplier: Anaspec Inc
Description: A synthetic peptide substrate specific for AMP-activated protein kinase (AMPK).
Sequence:HMRSAMSGLHLVKRR-NH2
MW:1778.2 Da
% peak area by HPLC:95
Storage condition:-20° C


Catalog Number: (10430-274)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Supplier: Cayman Chemical Company
Description: 3 3-cGAMP (sodium salt), Purity: >/=98%, Appearance: Crystalline solid, Second messenger, Synonyms: 3',3'-Cyclic GMP-AMP, Adenosine-Guanosine 3',3'-cyclic monophosphate, Adenylyl-(3'?5')-3'-guanylic acid, cyclic nucleotide, disodium salt, c-GpAp, Size: 100ug

Catalog Number: (10395-408)
Supplier: Bioss
Description: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.


Catalog Number: (10395-414)
Supplier: Bioss
Description: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.


Catalog Number: (89350-018)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to AMPK alpha 2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)


Catalog Number: (76117-714)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Supplier: New England Biolabs (NEB)
Description: Apyrase (recombinant, E.coli) is a highly active ATP-diphosphohydrolase that catalyses the sequential hydrolysis of ATP to ADP and ADP to AMP releasing inorganic phosphate.

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Supplier: MilliporeSigma
Description: A key regulator of many cellular reactions.
Supplier: Alere
Description: Rapid Drug Screen for the simultaneous, qualitative detection of single or multiple drug metabolites in human urine

Catalog Number: (89349-854)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to DAK (bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing))


Supplier: TRESTON IAC LLC
Description: Quick Ship dimension 4 electrical channel assembly, includes three (3) duplex outlets, on/off switch with pilot light, 15-amp circuit breaker and 8ft power cord, UL Listed

UL Listed cUL Listed CSA Certified

Catalog Number: (10336-554)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism.


Supplier: Thermo Scientific Chemicals
Description: Crystalline powder
Supplier: Clarity Diagnostics
Description: Integrated drug panel and testing cup in one.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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