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Supplier: MP Biomedicals
Description: Adenosine 5′-monophosphate is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenine.

SDS

Catalog Number: (75796-250)
Supplier: Germaine Laboratories
Description: AimScreen™ Single-Drug Dipdevices are a single-step immunoassay designed for the qualitative detection of drugs of abuse in urine


Catalog Number: (470016-030)
Supplier: Wards
Description: A convenient design for AC and DC experiments up to 5 amps.


Catalog Number: (77511-050)
Supplier: AFG Bioscience
Description: Mouse CREB (Cyclic AMP Response Element Binding Protein) ELISA Kit

New Product


Catalog Number: (PAV1682)
Supplier: Promega Corporation
Description: The cAMP-Glo Max Assay is a homogeneous, bioluminescent and high-throughput assay to measure cyclic AMP (cAMP) levels in cells. Compounds that modulate GPCRs coupled with adenylate cyclase typically alter intracellular cAMP levels.


Catalog Number: (76110-732)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism. Involvement in diseaseDefects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE); also known as erythrocyte AMP deaminase deficiency. AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders.


Supplier: Zymo Research
Description: <p>The Mix & Go!™ <em>E. coli</em> transformation kit and Mix & Go!™ <em>E. coli </em>transformation buffer set are convenient methods for the preparation of competent<em> E. coli </em>cells for simple and highly efficient DNA transformation.</p>

Supplier: Molecular Devices
Description: CatchPoint® Cyclic-AMP Fluorescent Assay Kit: Cell signaling via G protein-coupled receptors (GPCRs) can be assessed by monitoring the downstream effectors calcium or cyclic AMP (<B>cAMP</B>).

Catalog Number: (10336-538)
Supplier: Bioss
Description: AMP deaminase plays a critical role in energy metabolism.


Supplier: StatLab
Description: <p>Slides for routine H&E or special stain applications.</p>

New Product

Supplier: ALADDIN SCIENTIFIC
Description: Adenosine 3′,5′-cyclic monophosphate sodium salt is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is an activator of Epac.Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.

New Product

Catalog Number: (103007-520)
Supplier: Anaspec Inc
Description: Dermcidin-1L (DCD-1L) is a 48-amino acid antimicrobial peptide (AMP) with a Leu residue on the C-terminus. It is expressed in eccrine sweat glands, secreted into sweat, and transported to the epidermal surface. Unlike most AMPs, which are cationic, DCD has a net negative charge.
Sequence:SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
MW:4818.5 Da
% peak area by HPLC:95
Storage condition:-20° C


Supplier: New England Biolabs (NEB)
Description: E.coli Poly(A) Polymerase catalyzes the template independent addition of AMP from ATP to the 3´ end of RNA.

Small Business Enterprise

Catalog Number: (10430-272)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Catalog Number: (10430-260)
Supplier: Bioss
Description: Probable inhibitory regulator of the Ras-cyclic AMP pathway.


Catalog Number: (10395-406)
Supplier: Bioss
Description: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.


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