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Catalog Number: (10272-480)
Supplier: Bioss
Description: Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.


Catalog Number: (76117-814)
Supplier: Bioss
Description: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.


Catalog Number: (77522-872)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968

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Catalog Number: (77524-538)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968

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Catalog Number: (10793-374)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to ARHGAP17 (Rho GTPase activating protein 17)


Catalog Number: (76011-262)
Supplier: Prosci
Description: ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).


Catalog Number: (76173-608)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Rho-associated protein kinase 2(ROCK2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.


Supplier: AFG BIOSCIENCE LLC
Description: 31472488

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Catalog Number: (77438-666)
Supplier: Bioss
Description: Transcription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B.


Catalog Number: (76173-004)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Rho guanine nucleotide exchange factor 1(ARHGEF1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.


Catalog Number: (75929-982)
Supplier: Rockland Immunochemical
Description: Moesin (or membrane-organizing extension spike protein) belongs to ERM family that modulates epithelial integrity by regulating cell-signalling events that affect actin organization and polarity (1). The effects of Moesin on epithelial cells appear to result from inhibition of Rho signaling. ERM proteins serve a structural role in linkage of the cytoskeletion to the plasma membrane and the rescue of cells lacking Moesin by modulation of Rho signaling indicates that inhibition of Rho activity may be a more critical function of Moesin. The negative feedback loop produced by Rho's activation of ERM may be an important mechanism that prevents the excessive migratory and invasive properties characteristic of metastatic cancer cells (2). Moesin Protein is ideal for investigators involved in Signaling Reagents, Protein Substrates, Inflammation, and PKA/PKC Pathway research.


Catalog Number: (10326-410)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.


Catalog Number: (10102-652)
Supplier: Prosci
Description: SYDE1 contains 1 Rho-GAP domain. It is a GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.


Catalog Number: (10462-586)
Supplier: Bioss
Description: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].


Catalog Number: (10462-568)
Supplier: Bioss
Description: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].


Supplier: AFG BIOSCIENCE LLC
Description: 31472488

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