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Supplier: ALPHA RHO, INC.
Description: Container, Plastic

Catalog Number: (103456-320)
Supplier: Affymetrix, Inc.
Description: GABRD is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This protein encodes the delta subunit.

Blocked

Catalog Number: (103495-064)
Supplier: Affymetrix, Inc.
Description: This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Blocked

Catalog Number: (77515-756)
Supplier: AFG BIOSCIENCE LLC
Description: Human ARHGDIa (Rho GDP Dissociation Inhibitor Alpha) ELISA Kit

New Product


Catalog Number: (103458-698)
Supplier: Affymetrix, Inc.
Description: This Antibody targets GABA A Receptor alpha 1 in WB applications and shows reactivity with Human samples. The immunogen is recombinant fragment corresponding to a region within amino acids 1 and 261 of Human GABA A Receptor alpha 1. This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Blocked

Catalog Number: (103453-542)
Supplier: Affymetrix, Inc.
Description: This antibody is predicted to react with bovine and rat based on sequence homology. This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Blocked

Catalog Number: (89318-444)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to RhoGDI (Rho GDP dissociation inhibitor (GDI) alpha)


Catalog Number: (103493-060)
Supplier: Affymetrix, Inc.
Description: This antibody is predicted to react with bovine and human based on sequence homology. This gene encodes a gamma-aminobutyric acid receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Blocked

Catalog Number: (10325-544)
Supplier: Bioss
Description: CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms.


Catalog Number: (103495-952)
Supplier: Affymetrix, Inc.
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha1-6, GABAA R beta1-3, GABAA R gamma1-3, GABAA R delta, GABAA R epsilon, GABAA R-rho-1 and GABAA R-rho-2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Blocked

Catalog Number: (10111-168)
Supplier: Prosci
Description: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit.


Catalog Number: (89359-574)
Supplier: Genetex
Description: GDP - Dissociation inhibitors (GDIs) modulate GTPase activity by binding to small G-proteins and regulating GDP/GTP exchange of inflammatory cell activity, including motility, formation of toxic oxygen metabolites and generation of proinflammatory cytokines. RhoGDI may also be critical for the cellular compartmentalization of GTPases. RhoGDI, which can bind to Rho, Rac, and cdc42, is localized in the cytosol. D4GDI, an abundant hematopoietic cell GDI for the Ras-related Rho family GTPases, is a substrate of the apoptosis protease.


Catalog Number: (10264-542)
Supplier: Bioss
Description: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.


Catalog Number: (10264-562)
Supplier: Bioss
Description: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.


Catalog Number: (10100-638)
Supplier: Prosci
Description: GABRG2 is a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.


Catalog Number: (89274-498)
Supplier: Genetex
Description: Mouse monoclonal antibody [1A7] to ARHGDIA


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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