Lenti-Pseudovirus_SARS-CoV-2 with Luciferase, ReVacc Scientific
Supplier: ReVacc Scientific
This pseudotyped virus uses Lentiviral vectors to package full length of S protein of SARS-CoV-2 (GenBank: MN908947).
Infection of cells with this pseudotyped virus carrying luciferase reporter results in detectable luciferase activity. See the titration result showing the undiluted pseudovirus generates signal ~150-fold higher than uninfected control (cell alone as background). The neutralizing activity of one control mAb was tested by using this pseudotyped virus.
The pseudotypes should be handled using BSL-2 containment practices. Applications include Anti-SARS-CoV-2 neutralizing antibody screening at high throughput, Anti-SARS-CoV-2 drug screening at high throughput and SARS-CoV-2 pseudovirus transduction of target cells for viral entry and functional studies.
Envase: Shipping with dry ice. Require −80 °C storage. Multiple freeze/Thaw cycles will reduce its sensitivity. Recommend only one cycle. Aliquot after the first thaw.
Precaución: Handle it in biosafety cabinet in BSL-2. Contacted tips and tubes should be decontaminated by 10% disinfecting bleach. For research use only.
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