JC-10 ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
Synonyms:
Enhanced JC-1
Derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (570 nm) in healthy cells. Upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (520 nm). Shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. Spectral data: lambdaex 510 nm| lambdaem 525.
Specification Test Results
Source/Host | Synthetic |
Purity |
|
Appearance/Color | Deep blue, violet crystals. |
Solubility | Soluble in DMSO or water. |
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