Asiaticoside ≥95% (by NMR)
Supplier: ADIPOGEN CORP MS
Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor.
Formula:
C₄₈H₇₈O₁₉ Storage Temperature: Refrigerator |
MDL Number:
MFCD06642601 CAS Number: 16830-15-2 |
Specification Test Results
Source/Host | Isolated from Centella asiatica. |
Purity |
|
Appearance/Color | White solid. |
Solubility | Soluble in ethanol, methanol or pyridine. Insoluble in water. |
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