BLZ-945 ≥95%
Supplier: ADIPOGEN CORP MS
Synonyms:
BLZ945, Sotuletinib, 4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide
SYN-1197-M001
SYN-1197-M005
SYN-1197-M010
102992-724EA
239.54
USD
102992-724
102992-726
102992-728
BLZ-945 ≥95%
BLZ-945
BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound.
Formula:
C₂₀H₂₂N₄O₃S MW: 398.5 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD28142668 CAS Number: 953769-46-5 |
Specification Test Results
Purity |
|
Appearance/Color | Solid. |
Solubility | Soluble in DMSO. |
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