PF-04979064 ≥95%
Supplier: ADIPOGEN CORP MS
SYN-1194-M001
SYN-1194-M005
SYN-1194-M010
102992-702EA
292.15
USD
102992-702
102992-704
102992-706
PF-04979064 ≥95%
PF-04979064
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM for the PI3K family when tested AKT phosphorylation in BT20 cells. In direct kinase assays, PF-04979064 has potent Ki values against PI3Kalpha (Ki= 0.13nM human, 0.299nM mouse) and PI3Kgamma (Ki=0.111nM), and PI3Kdelta (Ki=0.122nM). In contrast, Ki values for non-PI3K kinases such as mTOR were 10X higher at 1.42 nM.
Formula:
C₂₄H₂₆N₆O₃ Storage Temperature: Refrigerator |
CAS Number:
1220699-06-8 |
Specification Test Results
Purity |
|
Appearance/Color | Solid. |
Solubility | Soluble in DMSO. |
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