AZD-26 ≥95%
Supplier: ADIPOGEN CORP MS
SYN-1160-M001
SYN-1160-M005
SYN-1160-M010
102992-456EA
292.15
USD
102992-456
102992-458
102992-460
AZD-26 ≥95%
AZD-26
AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.
Formula:
C₂₂H₂₁N₃O Storage Temperature: Freezer |
CAS Number:
1357158-81-6 |
Specification Test Results
Purity |
|
Appearance/Color | Solid. |
Solubility | Soluble in DMSO or ethanol. |
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