R428 ≥95%

Supplier: ADIPOGEN CORP MS

Synonyms: (S)-1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)-1H-1,2,4-triazole-3,5-diamine, Bemcentinib

SYN-1131-M001 SYN-1131-M005 SYN-1131-M010
102992-254EA 373.85 USD
102992-254 102992-256 102992-258
R428 ≥95%
R428

R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .

Formula: C₃₀H₃₄N₈
MW: 506.6 g/mol
Storage Temperature: Freezer
MDL Number: MFCD21608463
CAS Number: 1037624-75-1

Order Now

Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR