PD-173955 ≥95%
Supplier: ADIPOGEN CORP MS
Synonyms:
6-(2,6-Dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one, PD173955
SYN-1061-M001
SYN-1061-M005
SYN-1061-M010
102991-732EA
246.46
USD
102991-732
102991-734
102991-736
PD-173955 ≥95%
PD-173955
PD173955 is an ATP-competitive, dual Src/Bcr-Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC(50) of 1-2nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 also inhibits Src kinase activity in vitro with an IC(50) of 22nM and could represent a novel class of anti-mitotic drug.
Formula:
C₂₁H₁₆Cl₂N₄OS MW: 443.4 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD16038305 CAS Number: 260415-63-2 |
Specification Test Results
Purity |
|
Appearance/Color | Solid. |
Solubility | Soluble in DMSO or ethanol. |
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