PD-173955 ≥95%

Supplier: ADIPOGEN CORP MS

Synonyms: 6-(2,6-Dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one, PD173955

SYN-1061-M001 SYN-1061-M005 SYN-1061-M010
102991-732EA 246.46 USD
102991-732 102991-734 102991-736
PD-173955 ≥95%
PD-173955

PD173955 is an ATP-competitive, dual Src/Bcr-Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC(50) of 1-2nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 also inhibits Src kinase activity in vitro with an IC(50) of 22nM and could represent a novel class of anti-mitotic drug.

Formula: C₂₁H₁₆Cl₂N₄OS
MW: 443.4 g/mol
Storage Temperature: Freezer
MDL Number: MFCD16038305
CAS Number: 260415-63-2

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

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