IC87114 ≥95%

Supplier: ADIPOGEN CORP MS
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Synonyms: 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one, IC-87114

SYN-1045-M001 SYN-1045-M005 SYN-1045-M010 SYN-1045-M050
102991-598EA 90 USD
102991-598 102991-600 102991-602 102991-604
IC87114 ≥95%
IC87114

IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.

Formula: C₂₂H₁₉N₇O
MW: 397.4 g/mol
Storage Temperature: Freezer
MDL Number: MFCD09970845
CAS Number: 371242-69-2

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO. Slightly soluble (1mg/ml) in ethanol.

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