BX-795 ≥95%

Supplier: ADIPOGEN CORP MS

Synonyms: BX795, N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide

SYN-1026-M001 SYN-1026-M005 SYN-1026-M010 SYN-1026-M050
102991-446EA 96.92 USD
102991-446 102991-448 102991-450 102991-452
BX-795 ≥95%
BX-795

BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368µM to greater than 450µM.

Formula: C₂₃H₂₆IN₇O₂S
MW: 591.5 g/mol
Storage Temperature: Freezer
MDL Number: MFCD12546134
CAS Number: 702675-74-9

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

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