ZnAF-1F ≥90% (by HPCE)

Supplier: ADIPOGEN CORP MS

Synonyms: 5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein

CDX-Z0009-M001 CDX-Z0009-M005 CDX-Z0009-M025

102991-238EA 193.85 USD

102991-238 102991-240 102991-242

ZnAF-1F ≥90% (by HPCE)

ZnAF-1F

ZnAF-1F and ZnAF-2F do not fluoresce in the presence of other biologically important cations such as Ca2+ and Mg2+, and are insensitive to change of pH. The complexes with Zn2+ of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2+ complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence under neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. Spectral data: lambdaex 492nm; lambdaem 517nm in PBS.

Formula: C₃₄H₂₆F₂N₄O₅
MW: 608.59 g/mol
Storage Temperature: Freezer

CAS Number: 443302-08-7

Specification Test Results

Source/Host	Synthetic.
Purity	90% (HPCE)
Appearance/Color	Solid.
Solubility	Soluble in DMSO.

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