5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95% (by HPLC)
Supplier: ADIPOGEN CORP MS
Synonyms:
Pim1/2 Inhibitor IV, (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione
Potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively) as well as DYRK1alpha (68% inhibition of DYRK1alpha and Pim-2 at 5 µM), while exhibiting little or no activity against a panel of 57 other kinases (
Formula:
C₁₃H₁₃NO₃S MW: 263.31 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD31382191 CAS Number: 587852-28-6 |
Specification Test Results
Source/Host | Synthetic |
Purity |
|
Appearance/Color | Yellow powder. |
Solubility | Soluble in DMSO. |
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