7-Azido-4-methylcoumarin

Supplier: ADIPOGEN CORP MS

Irritant Warning

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Synonyms: 7-Azido-4-methyl-1-benzopyran-2-one

CDX-A0069-M001 CDX-A0069-M010 CDX-A0069-M050

102989-174EA 70.62 USD

102989-174 102989-176 102989-178

7-Azido-4-methylcoumarin

7-Azido-4-methylcoumarin

7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators.

Formula: C₁₀H₇N₃O₂
MW: 201.2 g/mol

MDL Number: MFCD16652405
CAS Number: 95633-27-5

Specification Test Results

Source/Host	Synthetic
Purity
Appearance/Color	Yellow powder
Solubility	Soluble in DMSO.

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