Butyrolactone I ≥98% (by HPLC, NMR)

Supplier: ADIPOGEN CORP MS
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BVT-0448-M001 BVT-0448-M005
102989-054EA 180 USD
102989-054 102989-056
Butyrolactone I ≥98% (by HPLC, NMR)
Butyrolactone I

Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.

Formula: C₂₄H₂₄O₇
Storage Temperature: Freezer
MDL Number: MFCD03453074
CAS Number: 87414-49-1

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Specification Test Results

Source/Host Isolated from Aspergillus terreus.
Purity 98% (HPLC, NMR)
Appearance/Color White to off-white solid.
Solubility Soluble in DMSO, methanol, ethanol or acetone.

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