cGAMP disodium salt ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
Potent STING ligand. Second messenger in human and mouse cells that triggers interferon production in response to cytosolic DNA. Binding to STING leads to activation of IRF3 (IFN regulatory factor 3) and the induction of interferon-beta. First cyclic nucleotide in metazoa. Plays a role in bacterial chemotaxis and colonization.
Specification Test Results
Source/Host | Synthetic. |
Purity | >98% (HPLC) |
Appearance/Color | Crystalline solid. |
Solubility | Soluble in water. |
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